ID A0A0F0KEC4_9MICO Unreviewed; 311 AA.
AC A0A0F0KEC4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Glyoxylate/hydroxypyruvate reductase A {ECO:0000313|EMBL:KJL19198.1};
DE EC=1.1.1.79 {ECO:0000313|EMBL:KJL19198.1};
GN Name=ghrA {ECO:0000313|EMBL:KJL19198.1};
GN ORFNames=RN50_02478 {ECO:0000313|EMBL:KJL19198.1};
OS Microbacterium foliorum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=104336 {ECO:0000313|EMBL:KJL19198.1, ECO:0000313|Proteomes:UP000033572};
RN [1] {ECO:0000313|EMBL:KJL19198.1, ECO:0000313|Proteomes:UP000033572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12966 {ECO:0000313|EMBL:KJL19198.1,
RC ECO:0000313|Proteomes:UP000033572};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL19198.1}.
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DR EMBL; JYIU01000045; KJL19198.1; -; Genomic_DNA.
DR RefSeq; WP_045254816.1; NZ_JYIU01000045.1.
DR AlphaFoldDB; A0A0F0KEC4; -.
DR KEGG; mfol:DXT68_03255; -.
DR PATRIC; fig|104336.4.peg.2527; -.
DR Proteomes; UP000033572; Unassembled WGS sequence.
DR GO; GO:0030267; F:glyoxylate reductase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KJL19198.1}; Pyruvate {ECO:0000313|EMBL:KJL19198.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033572}.
FT DOMAIN 98..281
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 311 AA; 32713 MW; 48927AC2FF918A94 CRC64;
MKVLIPNTIE LPLTADVDAV VYDTSADIPD EHRDAEMLVV WGNSASWLQN AAGSLPRLRL
VQALASGADA VLNAGFGSEV RICSGRSLHD GPVAEHALAL ILSAVRRIDR LRDAQREHRW
DDAFNQEQAA SATRAHHTLD GAHVTIWGFG SIASTLAPLL AALGAQVEGI ARTAGHRAGF
EVHADADAPA LLAQTDVLVS ILPATDATAD LFDAEVFGAL KRGAVFVNVG RGATVDETAL
IDALESGQLR AAAIDVAKAE PLPASDPLWD TPNLLLTPHV AGNRPVGAAD LVDENIARLR
AGDELVNQVH P
//
