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Database: UniProt
Entry: A0A0F2J2F0_9BACT
LinkDB: A0A0F2J2F0_9BACT
Original site: A0A0F2J2F0_9BACT 
ID   A0A0F2J2F0_9BACT        Unreviewed;       490 AA.
AC   A0A0F2J2F0;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   28-MAR-2018, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=MCHI_001565 {ECO:0000313|EMBL:KJR42538.1};
OS   Candidatus Magnetoovum chiemensis.
OC   Bacteria; Nitrospirae; Nitrospirales; Nitrospiraceae;
OC   Candidatus Magnetoovum.
OX   NCBI_TaxID=1609970 {ECO:0000313|EMBL:KJR42538.1, ECO:0000313|Proteomes:UP000033718};
RN   [1] {ECO:0000313|EMBL:KJR42538.1, ECO:0000313|Proteomes:UP000033718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS-04 {ECO:0000313|EMBL:KJR42538.1,
RC   ECO:0000313|Proteomes:UP000033718};
RA   Kolinko S., Richter M., Glockner F.O., Brachmann A., Schuler D.;
RT   "Single-cell genomics of uncultivated deep-branching MTB reveals a
RT   conserved set of magnetosome genes.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KJR42538.1}.
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DR   EMBL; JZJI01000412; KJR42538.1; -; Genomic_DNA.
DR   EnsemblBacteria; KJR42538; KJR42538; MCHI_001565.
DR   Proteomes; UP000033718; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033718};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033718}.
FT   DOMAIN      396    464       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     193    200       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   490 AA;  55861 MW;  109A4C32F48D4FED CRC64;
     MESVWNQVKI NIQSMLPDHS FRMWIQPIQF FSFENSITTL ICPNIFSKKR VKDNYLKIIL
     EEFSKLGHSD IKIEINIDEK RKINSNQKIH QKVHEKSISA YSNNGGKRLT SENANPVLGQ
     KSNNIIIRRH QSDSDQQLSL PGLPRSFDTG RMLRKDYTFD HFVVGNNNDF AYSASLSLAQ
     SGNAANNSLY ILADTGLGKS HLSQAVGHHV IEQGITNRVF YITAEDFTNE MIHSIQNKSI
     SLFKEKYRRK CDVLILEDIH FLSGKEATQK ELAITLDYLL NSDKKVIFSG CYLPCDIPKI
     NEQLKSRLTM GLVTKIEAPD FETRVKILNK KSRINGYKIS RDVIEYIAQE LCDNVRQLES
     GLTGIVAKGS LMGEKIDTNL ARSVIETISN NRQRITINSI KKLICNEFAI SESDLLSNSR
     KTKLVHPRQI AIYLSRKHTE QSLKVISKSF NRYHATAIYS INAVEKAIKQ QGALYEQLNY
     LNKKIETGKL
//
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