ID A0A0F2LRB2_SPOSC Unreviewed; 574 AA.
AC A0A0F2LRB2;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Protein SDS23 {ECO:0000256|ARBA:ARBA00014106};
DE AltName: Full=Protein sds23 {ECO:0000256|ARBA:ARBA00020584};
GN ORFNames=SPSK_00470 {ECO:0000313|EMBL:KJR80042.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR80042.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR80042.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR80042.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR80042.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR80042.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- FUNCTION: Involved in DNA replication and cell separation.
CC {ECO:0000256|ARBA:ARBA00002656, ECO:0000256|PIRNR:PIRNR018148}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR018148}.
CC -!- SIMILARITY: Belongs to the SDS23 family.
CC {ECO:0000256|ARBA:ARBA00006624, ECO:0000256|PIRNR:PIRNR018148}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR80042.1}.
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DR EMBL; AXCR01000012; KJR80042.1; -; Genomic_DNA.
DR RefSeq; XP_016582718.1; XM_016727439.1.
DR AlphaFoldDB; A0A0F2LRB2; -.
DR GeneID; 27662716; -.
DR KEGG; ssck:SPSK_00470; -.
DR VEuPathDB; FungiDB:SPSK_00470; -.
DR OrthoDB; 1449566at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042149; P:cellular response to glucose starvation; IEA:UniProtKB-UniRule.
DR GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR016711; Ssd23.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF163; PROTEIN SDS23-RELATED; 1.
DR Pfam; PF00571; CBS; 1.
DR PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR018148}.
FT DOMAIN 295..352
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 60507 MW; AEBC281BBC06CE2C CRC64;
MESSTPPTAE RGAGGAATGS GSSSTSSLNV GGATQTSSGS TAGAVPERSP SRSSLRHSHS
HSHSSSSHRQ SFAENLRNPP PSPRSLRQPS FATQVHGLLN HPPPQRQPNP RFAGRDWHDI
SLGELVSEED IRWATLDTSV EDCTKTLLRN SSTAGAVLVR NGLSDKMAVS TFDYNDLNAY
LLVVIGMANP DPEQVIVYQS IAQRAQDRVA IPIRDVLPIC HKEPLATLSY NDDLLAAIEV
FGSGARRVIV TNANATEVVG VLSQLQLIQF FWNEAVNFPQ IDRLYAATLR DLRIGSQEII
AINADRPLSD ALTLMNSEGL TSVAVVDNGL NVVGNISTRD VQHLTSVTSF PLLQSSCMHF
ISVILSERGV EEGRDSFPVF HVNPHSTLAH TVAKLVATRA HRMWVVESPS PSPSAPHTPL
LSPVQTASST VSSASIATPS GSGHSRTASG TGIPGGPTTA NGTGEGHSRR ESTVLTTAAT
TVTVAPQSPI PLPGGNGGNA PAFASVPASS LPGAHLSGRL TGVVSLTDIL NLFAKTTGLR
PSDPADIRAR RRRSSSSSLR PSIDGARTSV DLRR
//
