ID A0A0F2LUA8_SPOSC Unreviewed; 988 AA.
AC A0A0F2LUA8;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000313|EMBL:KJR81063.1};
GN ORFNames=SPSK_04892 {ECO:0000313|EMBL:KJR81063.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR81063.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR81063.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR81063.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR81063.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR81063.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR81063.1}.
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DR EMBL; AXCR01000012; KJR81063.1; -; Genomic_DNA.
DR RefSeq; XP_016583739.1; XM_016731652.1.
DR AlphaFoldDB; A0A0F2LUA8; -.
DR GeneID; 27666929; -.
DR KEGG; ssck:SPSK_04892; -.
DR VEuPathDB; FungiDB:SPSK_04892; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Ribonucleoprotein {ECO:0000313|EMBL:KJR81063.1}.
FT DOMAIN 132..318
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 988 AA; 109770 MW; 8651CD7228EC3C0B CRC64;
MDDLYDEFGN FIGEEPEASD EGSEQGDADA DNYVYGDDEE VGEDGVGQEL MEVDDEGPSN
AVILHEDKQY YPTAAQVYGS EVEALVQEED AQPLSEPIVA PVEQKKFVVE EADLPPVFFD
RGFMADLMNF PEQIRNVAFA GHLHHGKTAF VDMLVLETHD IGERLEQRSG RSRDEQLRYT
DVHVLERERG VSTRSAPMSL VLPSTKGKSH LINLIDTPGH VDFADEVASA LRLVDGVCLV
VDVVEGVQLH TEMVVRHAML EGLPLTLIVN KVDRLILELK LPPTDAYYKL KSTIEAVNKV
IFETLPGETD DRKRVSPEKG NVLFACTDMK WCFTLASFAK MYADSFGAMD TGEFAKRLWG
DVFFNPKKRS FTRKAVEDNA KRSFVHFVLE PIYKLFTHTI SENPQDLKAF LAPLGIALKP
SQYKADARVL LNLVCAQFFG PPAAFVDMVV AHVPSPVEAS ARHLQRYYTG PLDTKVAESI
GACDQDGPLV MEVTKLYSAP DAKSFHALGR VFSGIARPGT EVRVLGEGYS LDDEEDMAPA
QISDVWIPET RYNVPTDGVP AGNWVLLGGV DNSIVKSATV VARHFADDED AYIFKPVTHY
TESVFKIAVE PVNPSELPKM LDGIRKINKS YPLITTKVEE SGEHILIGTG EMYMDCVMHD
LRLQYADMEI KVSDPLTRFC ETVVDESATR CWTLTPNKKN RLTMVAEPLE EGLAGDIESG
AVRIKDPVRK TAKFLQDKYD WDLLASRSVW AFGPEEMGAN LLQDDTLPGE VDKKMLNTVK
ESIRQGFSWA TREGPLCEEP IRNIKFKLTD VTLAQETIYR GGGQIIPTAR RACYGSFMLS
SPRLMEPVYT VSMTGPEAAS SKLYQILSQR RGHVLTDVGI PGTNLSRTVG LLPVIDSFGF
ETDFRISSDN TGLVSLVFDR WQVVPGDPLD RDVILRPMQM APVQGTARDF VLKTRKRKGL
SEDVSIGKFL EPELYSELVS SGTLEEGS
//
