ID A0A0F2M2M6_SPOSC Unreviewed; 1077 AA.
AC A0A0F2M2M6;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE RecName: Full=MINDY deubiquitinase domain-containing protein {ECO:0000259|Pfam:PF04424};
GN ORFNames=SPSK_00219 {ECO:0000313|EMBL:KJR83948.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR83948.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR83948.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR83948.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR83948.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR83948.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR83948.1}.
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DR EMBL; AXCR01000008; KJR83948.1; -; Genomic_DNA.
DR RefSeq; XP_016586624.1; XM_016727197.1.
DR AlphaFoldDB; A0A0F2M2M6; -.
DR GeneID; 27662474; -.
DR KEGG; ssck:SPSK_00219; -.
DR VEuPathDB; FungiDB:SPSK_00219; -.
DR OrthoDB; 9158at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:1990380; F:K48-linked deubiquitinase activity; IEA:InterPro.
DR InterPro; IPR007518; MINDY.
DR InterPro; IPR033979; MINDY_domain.
DR PANTHER; PTHR18063; NF-E2 INDUCIBLE PROTEIN; 1.
DR PANTHER; PTHR18063:SF6; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF04424; MINDY_DUB; 1.
PE 4: Predicted;
FT DOMAIN 499..649
FT /note="MINDY deubiquitinase"
FT /evidence="ECO:0000259|Pfam:PF04424"
FT REGION 1..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 773..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..1077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..161
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1015..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1077 AA; 115504 MW; 82623106CE350B79 CRC64;
MPNMVVRKPL PQTYDGTGSG SPGGVNSDSV PDVLRPGRNP HPNAYSPAPP SPYSNFQTDE
QSAWAQPAPP AMPQGITSQN DSSQQPTPQQ QPPPIPTAVP TILLQSATGS STASGFSETN
PFKRKAVMSA ESPVQSPAVA VPPLPSAPAP PPPPPASQPL PPTTSFSQLS MDDQTGNPWQ
PTPIDSRRGS QAPIPVIPEN EAVGGGENAW ASQNATESPF RRPSPNPAAS NRDSNLISFP
PDEDADIAGW DEVASPVAAP GAGAASLPPP RPPFTPLNGK ETASDSNPVF EDRNAWDDLG
ARSGQPQPLP TNLVTEPAGE GWNLVDNEPV PGQLSRQSTW ENFTDDEEDV EQPNSSQAKP
AKPPLKPKPK NKNKLKEKNV VPSVPVGAVD TSAPLISIDS PPPTSKPDEP VPAAAPTDSL
QAVSQEAEEP APLLPPRSML DVDGDTPPRQ PPRPSQSAKA ETYQVKNISW YDVSASQNPR
VSPILVQNAN GPCPLVALVN ALTLTTPADI STALVETLRS REQVSLSFLL DAVFDELMSS
RRSSRNSDLP DVDELYKFLK GLHTGMNVNP RFIPTQQVIT AFRRTSLTHL HPTERDDMIP
GTFEDTREMQ LYATFSIPLI HGWLPKKGDG AYEALSRQAA SYEDVQNLLF REEELEEKLS
SPSGDGLTED EQQVFQDILE IKNFLHGSAT QLTPFGLDIV AKAMRPGTFA ILFRNDHFST
LYRHPQTMQL LSLVTDAGYA SHDEVIWETL VDVNGEHAEF YSGDFRLVGN SMQQNASSGT
AGSGSRHGGS ASNNQNGWTT VRGRRQNQSE QHESHSPLLS NDELSRHEQE DRDLALALQL
QEEEEEQQRA DEAHRNSRLS EQFIEQNARP ANQSRRPSNA AGGGRYNSSQ PVPVSSRRSS
AGFPPGSLLD SNPNHRRTSS SSASGSALGS TMSNGQRIGQ YSSGRTPSRS PSHQQVVRPL
VPPTSTSRVN TRPAVNRPAD NDENDEAPPS YEQAAKLAPY HPPPGAPGSE SAAGGRNSAA
GSSSNLGGSS RASISTPSPR PLGGYATTSG RQNFAPGTYS AYQQQQAARS DRDCTIM
//
