ID A0A0F2M3C0_SPOSC Unreviewed; 463 AA.
AC A0A0F2M3C0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN ORFNames=SPSK_03364 {ECO:0000313|EMBL:KJR82636.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR82636.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR82636.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR82636.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR82636.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR82636.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR82636.1}.
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DR EMBL; AXCR01000010; KJR82636.1; -; Genomic_DNA.
DR RefSeq; XP_016585312.1; XM_016730202.1.
DR AlphaFoldDB; A0A0F2M3C0; -.
DR GeneID; 27665479; -.
DR KEGG; ssck:SPSK_03364; -.
DR VEuPathDB; FungiDB:SPSK_03364; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF66; ETHANOLAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KJR82636.1};
KW Transferase {ECO:0000313|EMBL:KJR82636.1}.
FT REGION 169..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 51030 MW; 52F54D9577FE22E9 CRC64;
MAFEPCNRHV PFVPLRYDSH DPESSALKLV LTLSPSWQLP GSSVEFIRFT DGITNTLLKA
VNRKPGLSQD AIDQDALLLR AYGHGTDLII DRQREAQNHE LLMQYGLAPT LLARFENGML
YRFIRGEVTR PEDIRRPEIS MAIARRLAQW HATVPCLPQA ITASISVDGR ISDGPSNGQP
HGGQNSDVQG STIAVASVSP NAGTPIAQGK LEPNIWTVMQ KWILALPADT AVCRERIAVL
QAELKSLVAS LSHRSGLGKD GLVFAHNDLL SGNIIILPAS AEATNGPPVE VTFIDYEYAV
PAPAAFDIAN HFAEWGGFDC NMNVLPTVEQ RRAFIDEYIN VYAKLRQLAP HGSEPFHLET
EKARMLEEVD VFRGVPGFYW GIWALIQATI SDIDFDYATY AEARLSEYWA WKAEVNGERA
ASGVDMPLRE RRWAQENEED NGGSSVATGS LQTRASTQST VPI
//
