ID A0A0F2MEI9_SPOSC Unreviewed; 401 AA.
AC A0A0F2MEI9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE RecName: Full=Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein {ECO:0000259|Pfam:PF01717};
GN ORFNames=SPSK_01790 {ECO:0000313|EMBL:KJR87275.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR87275.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR87275.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87275.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR87275.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87275.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR87275.1}.
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DR EMBL; AXCR01000005; KJR87275.1; -; Genomic_DNA.
DR RefSeq; XP_016589951.1; XM_016728692.1.
DR AlphaFoldDB; A0A0F2MEI9; -.
DR GeneID; 27663969; -.
DR KEGG; ssck:SPSK_01790; -.
DR VEuPathDB; FungiDB:SPSK_01790; -.
DR OrthoDB; 5488137at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF2; SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
FT DOMAIN 179..373
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 401 AA; 44258 MW; 0D5F5973C0A50176 CRC64;
MAPPFRAEHM GSLLRPQPLL DAREAVRQGQ TAEAAGLPAT EAKAVAEVVQ LQRDLGFRAV
GDGEFVRTRF WGLTWDEFDG TTRLQDADAS LFRLYHPDVV SLIEPGRQVM PGDSVIAGGK
LRHNPAKSVS NLHELQLIQA SLPKEHWADI KLTMITPAWF HMRYKQGKAY APEAYDSDAA
YFADVAAVYQ AELRQLYDAG LRNVQFDDPG LAYFCSAAFR EGWAADPDNV GSVDDLLDAY
IQLYNDALAG LPADLHTGVH LCRGNFIGGR HFAEGAYDII AQKLFQTLNV HTFYLEYDTA
RAGGFEPLAF LPPHKNVVVG AISTKLRALE DKEEVKARIH QAAAFVAKGR GQTEQEALQS
IAISPQCGFS THESGYPLRP EDQRAKLALV RTIADEIWGE P
//
