ID A0A0F2RPT7_9RHOB Unreviewed; 944 AA.
AC A0A0F2RPT7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:KJS40649.1};
GN ORFNames=VR71_21900 {ECO:0000313|EMBL:KJS40649.1};
OS Roseovarius sp. BRH_c41.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1629709 {ECO:0000313|EMBL:KJS40649.1, ECO:0000313|Proteomes:UP000033676};
RN [1] {ECO:0000313|EMBL:KJS40649.1, ECO:0000313|Proteomes:UP000033676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRH_c41 {ECO:0000313|EMBL:KJS40649.1};
RA Bagnoud A., Chourey K., Hettich R.L., de Bruijn I., Andersson A.F.,
RA Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT "Microbial metabolic network in the subsurface.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJS40649.1}.
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DR EMBL; LADY01000065; KJS40649.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F2RPT7; -.
DR PATRIC; fig|1629709.5.peg.4179; -.
DR Proteomes; UP000033676; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02783; MopB_CT_2; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.200.210; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..76
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 944 AA; 104953 MW; AD5CF0C948CB152C CRC64;
MTHQPRIDTS PHVSDEVRKT TCYMCACRCG INVHMKAGPD GKKHVAYIEG NRDHPVNKGV
LCAKGSAGIM QVNAPSRLRA PLKRVGPRGS GEFVEISWDE ALQIACDWLE PIRHEDPSKL
AFFTGRDQSQ SFTSFWAQNF GTPNYAAHGG FCSVNMAAAG IYTMGGAFWE FGQPDWDHTK
LFMLFGVAED HDSNPIKMGI GRIKARGARV IGVNPIRSGY NAVADDWVGI TPGTDGLFIL
SLIHELMRAG KIDLDYLARY TNAPVLVNAD SASPDHGLFL RDTDGKPLVI DRETGQLTAF
DKPGVRPDLS ATYDSDGITH RPVMHLMAER YLDPQYAPEA VAERCGITPD KIRRIAAEIA
RVAFEEEIAL DHEWTDFRGE THKTMIGRPV SFHAMRGISA HSNGFQTCRA LHVLQILLGT
IEVPGGFRFK PPYPKPVSAH PKPHCGVQPD CPLDGPHLGF VRGPEDLALK PDGTPARIDK
AFTWENPMSS HGLMHMVISN AHAGDPYKID TLFMYMANMS WNSSMNTSGV MDMLTDTDET
GEYVIPRIIY SDAYSSEMVA YADLILPDTT YLERHDCISL LDRPICEADA AADAIRWPVI
APDRDVRGFQ TVLVQLANKL KLPGFTTEDG SAKYADYADY IVNHERKPGI GPLAGFRGDG
TETGRGAPNP AQLDRYIENG GFYVSHIPEG ANYYKPWNMA YQDWAVGMGL FDTPQPYVFD
IYVETLRRFQ LAAEGHGDRQ PPDHLRERIK STLDPLPIWY PPFEDDSVST DEFPVHALTQ
RPMAMYHSWG TQNAWLRQIH GHNPLYLPTK IWQQHGFTDG DWARVTSAHG EITVPVAHMA
ALNENTVWTW NAIGKRKGAW ALSEDAPEAT RGFLLNHLIH ELLPPKGDGL RWSNSDPITG
QAAWFDLRVK ITRTDTPSEA KPIFAPLKSP VPQGPSHLEW KVGK
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