ID A0A0F3GRR5_9BACT Unreviewed; 1069 AA.
AC A0A0F3GRR5;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Bacillolysin {ECO:0000313|EMBL:KJU84462.1};
GN ORFNames=MBAV_003348 {ECO:0000313|EMBL:KJU84462.1};
OS Candidatus Magnetobacterium bavaricum.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Magnetobacterium.
OX NCBI_TaxID=29290 {ECO:0000313|EMBL:KJU84462.1, ECO:0000313|Proteomes:UP000033423};
RN [1] {ECO:0000313|EMBL:KJU84462.1, ECO:0000313|Proteomes:UP000033423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM-1 {ECO:0000313|EMBL:KJU84462.1};
RA Kolinko S., Richter M., Glockner F.O., Brachmann A., Schuler D.;
RT "Single-cell genomics of uncultivated deep-branching MTB reveals a
RT conserved set of magnetosome genes.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M4 family.
CC {ECO:0000256|ARBA:ARBA00009388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJU84462.1}.
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DR EMBL; LACI01001439; KJU84462.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F3GRR5; -.
DR PATRIC; fig|29290.4.peg.4434; -.
DR Proteomes; UP000033423; Unassembled WGS sequence.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09597; M4_TLP; 1.
DR Gene3D; 2.40.128.340; -; 1.
DR Gene3D; 3.10.170.10; -; 1.
DR Gene3D; 3.10.450.490; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR011096; FTP_domain.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR023612; Peptidase_M4.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR InterPro; IPR001570; Peptidase_M4_C_domain.
DR InterPro; IPR013856; Peptidase_M4_domain.
DR PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR PANTHER; PTHR33794:SF1; BACILLOLYSIN; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR Pfam; PF07504; FTP; 1.
DR Pfam; PF20773; InhA-like_MAM; 1.
DR Pfam; PF01447; Peptidase_M4; 1.
DR Pfam; PF02868; Peptidase_M4_C; 1.
DR PRINTS; PR00730; THERMOLYSIN.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 2.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000033423};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 126..174
FT /note="FTP"
FT /evidence="ECO:0000259|Pfam:PF07504"
FT DOMAIN 270..389
FT /note="Peptidase M4"
FT /evidence="ECO:0000259|Pfam:PF01447"
FT DOMAIN 392..558
FT /note="Peptidase M4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02868"
FT ACT_SITE 382
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
FT ACT_SITE 472
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
SQ SEQUENCE 1069 AA; 116860 MW; 8A3A87030FCCD886 CRC64;
MVYHKLVTNT IDYLISVKRG DFDMRKGKIF MSLLLLLFIA CCLDRSDLWA ASTDDALVQR
LRQTAGGQVV LAYHAGTGKV RFMRFEGTGT VPRARGLTEN ASAEVVARGF LDEYGRLFGV
EDQGQELKVM RQIMPEDGRS IVRFQQVYDN IPVMAGELIV QMDAKKNVLS ANGETSPMSV
VNTTPSIGHD AAKSEALNLI SKHYDISRTR LSVDDPQLWI YNPVLLGPGR NANTLVWRLE
VKANTPQPIH ELVLVDAHTG RIALHFNQTR DAKNRAVYDK NNVRDDKLPG NTPVRSEGQA
AVGIKDADDA YTYIGNTYDF YYNIHGRDSY DNEGSRIVAT VRYCPEDKKE ECPYDNAYWN
SGIKQFVFGS GYASADDVIA HEYTHGVTSS TSNLFYYYQS GAIDESFSDV WGEFVDQTNG
HGNDTASVKW LLGEDLPNGA IRNMKDPTAF KDPDKMGSAN YYCSSKDNGG VHTNSGINNK
AAYLMTDGDT FNSKTVTGIG IIKAAKIYYE ANSHLLISGS DYEDLYNALQ GACNTLINSS
VVTSSDCQQV KNTLDAVEMN RQPTGCPANE APVCDSGSPR DVFFDDLESG PGKWTHSAIV
GTDPWNAHTT GYATSGKYII YGEELKELSD SAIMMTTPVV IPQKAYMHFN HAYELEADTD
KALAQDIGRV AYSTDNGASW TDAGPLFTHN GYNLKSQHDG GYGFSDVSNG YISSRLDLSS
LAGKSVKFRF NLKTDVGTAY FGWIIDDVRI YTCDGGTATK PKTTMDLDGN GKSDILWYNT
VSGSARVWLM NDIKIASDSA IHTLPDLSWQ IKGSGDFNGD GKSDILWYNT SMGMVYIWFM
SGASVSSQGV VATLSDLSWQ IKGAGDFNGD GKSDILWYNT STGMVYIWFM SATLVSSQGT
VGTQPDLTWQ IKGAGDFNGD GKSDILWQNT KTGLVYIWYL SGTSITSANS PLTLSNLTWQ
IKGIGDFNGD GKSDILWYNP STGMLYTWLI NGGVIDSGSP AILPSNMKVV DIGDFNGDGK
SDICITDTST GQLYIGLMDG TKATSVGLSG TLNDSTWKVI PDGSNIPLF
//
