ID A0A0F3II09_9GAMM Unreviewed; 316 AA.
AC A0A0F3II09;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Malonyl CoA-acyl carrier protein transacylase {ECO:0000256|ARBA:ARBA00018953, ECO:0000256|PIRNR:PIRNR000446};
DE EC=2.3.1.39 {ECO:0000256|ARBA:ARBA00013258, ECO:0000256|PIRNR:PIRNR000446};
GN ORFNames=VZ94_11265 {ECO:0000313|EMBL:KJV06440.1};
OS Methylocucumis oryzae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylocucumis.
OX NCBI_TaxID=1632867 {ECO:0000313|EMBL:KJV06440.1, ECO:0000313|Proteomes:UP000033684};
RN [1] {ECO:0000313|Proteomes:UP000033684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sn10-6 {ECO:0000313|Proteomes:UP000033684};
RA Pandit P.S., Pore S.D., Arora P., Kapse N.G., Dhakephalkar P.K.,
RA Rahalkar M.C.;
RT "Draft genome sequence of a novel methanotroph (Sn10-6) isolated from
RT flooded ricefield rhizosphere in India.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KJV06440.1, ECO:0000313|Proteomes:UP000033684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sn10-6 {ECO:0000313|EMBL:KJV06440.1,
RC ECO:0000313|Proteomes:UP000033684};
RX PubMed=26547566; DOI=10.1007/s00248-015-0699-z;
RA Rahalkar M.C., Pandit P.S., Dhakephalkar P.K., Pore S., Arora P., Kapse N.;
RT "Genome Characteristics of a Novel Type I Methanotroph (Sn10-6) Isolated
RT from a Flooded Indian Rice Field.";
RL Microb. Ecol. 71:519-523(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP];
CC Xref=Rhea:RHEA:41792, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57384, ChEBI:CHEBI:64479,
CC ChEBI:CHEBI:78449; EC=2.3.1.39;
CC Evidence={ECO:0000256|ARBA:ARBA00000936,
CC ECO:0000256|PIRNR:PIRNR000446};
CC -!- SIMILARITY: Belongs to the fabD family.
CC {ECO:0000256|PIRNR:PIRNR000446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJV06440.1}.
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DR EMBL; LAJX01000111; KJV06440.1; -; Genomic_DNA.
DR RefSeq; WP_045779303.1; NZ_LAJX01000111.1.
DR AlphaFoldDB; A0A0F3II09; -.
DR PATRIC; fig|1632867.3.peg.382; -.
DR OrthoDB; 9808564at2; -.
DR Proteomes; UP000033684; Unassembled WGS sequence.
DR GO; GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR024925; Malonyl_CoA-ACP_transAc.
DR InterPro; IPR004410; Malonyl_CoA-ACP_transAc_FabD.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR NCBIfam; TIGR00128; fabD; 1.
DR PANTHER; PTHR42681; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42681:SF1; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR PIRSF; PIRSF000446; Mct; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|PIRNR:PIRNR000446};
KW Reference proteome {ECO:0000313|Proteomes:UP000033684};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000446}.
FT DOMAIN 11..306
FT /note="Malonyl-CoA:ACP transacylase (MAT)"
FT /evidence="ECO:0000259|SMART:SM00827"
FT ACT_SITE 96
FT /evidence="ECO:0000256|PIRSR:PIRSR000446-1"
FT ACT_SITE 206
FT /evidence="ECO:0000256|PIRSR:PIRSR000446-1"
SQ SEQUENCE 316 AA; 34339 MW; BCAB1D9D74591428 CRC64;
MSKKLYNLAF VFPGQGSQSV GMMNNLAAVY PEVRQTFTEA SDVLGFDLWQ IVTEDADKQL
DQTRYTQPAM LTAGVAIWRI WCQQSAIRPG WVAGHSLGEY TALICAEALA FADGLRLVAE
RGRLMQEAVP EGQGAMAAIL GLEDHIVVNL CHSLSSDANV VSAVNFNSPG QVVIAGHVDA
VTNAMAEAKR LGAKRALPIP VSVPSHCQLM QSAAEKLGEY LKSVTITTPK ATLIHNVDVV
SHDAPDVIKN ALIEQLYKPV RWSDSIKFMH EQGVTCFVEF GPGKVLQGLN KRIVKEAEHL
AIYDQQTLEH AGAFCT
//
