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Database: UniProt
Entry: A0A0F3L8V5_9CAUL
LinkDB: A0A0F3L8V5_9CAUL
Original site: A0A0F3L8V5_9CAUL 
ID   A0A0F3L8V5_9CAUL        Unreviewed;       484 AA.
AC   A0A0F3L8V5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=VH88_12425 {ECO:0000313|EMBL:KJV39948.1};
OS   Brevundimonas sp. KM4.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Brevundimonas.
OX   NCBI_TaxID=1628191 {ECO:0000313|EMBL:KJV39948.1, ECO:0000313|Proteomes:UP000033583};
RN   [1] {ECO:0000313|EMBL:KJV39948.1, ECO:0000313|Proteomes:UP000033583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KM4 {ECO:0000313|EMBL:KJV39948.1,
RC   ECO:0000313|Proteomes:UP000033583};
RA   Sulaiman J., Priya K., Chan K.-G.;
RT   "Draft genome sequence of Brevundimonas sp. KM4.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KJV39948.1}.
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DR   EMBL; JZRG01000022; KJV39948.1; -; Genomic_DNA.
DR   RefSeq; WP_045811538.1; NZ_JZRG01000022.1.
DR   EnsemblBacteria; KJV39948; KJV39948; VH88_12425.
DR   PATRIC; fig|1628191.3.peg.1180; -.
DR   Proteomes; UP000033583; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033583};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033583}.
FT   DOMAIN      174    302       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     182    189       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   484 AA;  52497 MW;  60CCAF42CBBA01CF CRC64;
     MAGGTKTSGL TDPDRIWSEA SVRLRAEIGD GPFSSYIAPS AVRLDNAGHL ILVTPTAYAR
     DWVRKNALRR MNELWLGLDG LSRRLEVRCR AEVGSAPPAS AVMPGNVVDA APRLAAFAAT
     PQMASAAPIS ADGARAVRAA GLQDRLTFDS FVEGQGNAFA LAIAKQVASW ADGHFNPVFF
     CGPYGYGKTH LLNAIAWEAQ RLRPEAKVVY LTAERFLSTF VKAMQDRSTA AFKESLRSAD
     MLLLDDVQFV GGKTSTQEEL LSTLTALIED GKRIVFSADR APMALTEVEP RLRSHLAAGL
     TCPVEAGDRE LKIAVAQNRL KALSALGVVQ GEANPEVLAQ LVDRTPGSMR ELEGAVNTLA
     AAAGARLSSV SVDEASTLLG MAMRGGPERR ITVDEIQKTV ADHFNMKQAD LLSERRTRSV
     ARPRQIAMYL CKQHTTRSYP DIGRRFGGRD HTTVLHGVRK IEELMPQDDQ IARDVEALTR
     KLRG
//
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