ID A0A0F4J8J4_9ACTN Unreviewed; 344 AA.
AC A0A0F4J8J4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KJY30109.1};
GN ORFNames=VR44_21195 {ECO:0000313|EMBL:KJY30109.1};
OS Streptomyces katrae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68223 {ECO:0000313|EMBL:KJY30109.1, ECO:0000313|Proteomes:UP000033551};
RN [1] {ECO:0000313|EMBL:KJY30109.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL ISP-5550 {ECO:0000313|EMBL:KJY30109.1};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY30109.1}.
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DR EMBL; JZWV01000589; KJY30109.1; -; Genomic_DNA.
DR RefSeq; WP_045949133.1; NZ_JZWV01000589.1.
DR AlphaFoldDB; A0A0F4J8J4; -.
DR STRING; 68223.GCA_002028425_02177; -.
DR PATRIC; fig|68223.7.peg.8962; -.
DR eggNOG; COG1609; Bacteria.
DR OrthoDB; 3324394at2; -.
DR Proteomes; UP000033551; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 344 AA; 36198 MW; 2E1AE20B7C7DA890 CRC64;
MTARLADIAA QAGVSEATVS RVLNGKPGVA AGTRESVLAA LDVLGYERPV RLRQRSAGLV
GLITPELDNP IFPALAQVIG QALTRQGYTP VLATQTPGGS TEDELTEMLV DRGVSGIIFV
SGLHADTTAD MGRYEQLRGQ GVPYVLINGF SDKVRAPFVS PDDRAAMQLA VTHLTALGHS
RIGLAVGPKR FVPVLRKIEG FRLAMKERLG LQEAEAEELI QHSLYTLEGG QAAAAALIGR
GCTAVVCASD MMALGAIRAA RQQGLRVPQD VSVVGFDDSP LIAFTDPPLT TIRQPVQAMG
QAAVRTLLEE IGGTPAPHSE FVFLPELVVR GSTASGPGQR RGPA
//
