ID A0A0F4KNU2_9LACO Unreviewed; 250 AA.
AC A0A0F4KNU2;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Transcriptional regulator, IclR family {ECO:0000313|EMBL:KJY48342.1};
GN ORFNames=JG29_14020 {ECO:0000313|EMBL:KJY48342.1};
OS Bombilactobacillus mellis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Bombilactobacillus.
OX NCBI_TaxID=1218508 {ECO:0000313|EMBL:KJY48342.1, ECO:0000313|Proteomes:UP000033695};
RN [1] {ECO:0000313|EMBL:KJY48342.1, ECO:0000313|Proteomes:UP000033695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hon2 {ECO:0000313|EMBL:KJY48342.1,
RC ECO:0000313|Proteomes:UP000033695};
RA Ellegaard K.M., Tamarit D., Javelind E., Olofsson T., Andersson S.G.,
RA Vasquez A.;
RT "Comparative genomics of the lactic acid bacteria isolated from the honey
RT bee gut.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY48342.1}.
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DR EMBL; JXBZ01000009; KJY48342.1; -; Genomic_DNA.
DR RefSeq; WP_045923231.1; NZ_KQ033878.1.
DR AlphaFoldDB; A0A0F4KNU2; -.
DR STRING; 1218508.JG29_14020; -.
DR PATRIC; fig|1218508.4.peg.1394; -.
DR HOGENOM; CLU_062618_6_3_9; -.
DR OrthoDB; 9791752at2; -.
DR Proteomes; UP000033695; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF35; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000033695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 7..69
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 70..250
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 250 AA; 28548 MW; 6D378127E86D7AD8 CRC64;
MEHKLYGTSI LKAKQIMDLL ADSTNGLSLN EISKKLVVSK PTILKILTTL TYIKYVRRNE
ENKRYYLGTV FIKYGNQTLN SFDISKSAYK YLDQLKNFTN ETVNLGIVDH DKIFILQKLN
GDQPINFNSQ VGDTMELYSS AMGKAALATM TAAQLDKYFS RNKLLSLTKY TITNIEQLKV
QLRDICNNGY AIDNQENQED VVCIGAAIEK YNKLFAAFSV STPQYRLNDS LFKDFINQVI
LTKQQIEQDL
//
