ID A0A0F4R7S3_9GAMM Unreviewed; 640 AA.
AC A0A0F4R7S3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nucleoside-diphosphate sugar epimerase {ECO:0000313|EMBL:KJZ15973.1};
GN ORFNames=TW85_03575 {ECO:0000313|EMBL:KJZ15973.1};
OS Marinomonas sp. S3726.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=579484 {ECO:0000313|EMBL:KJZ15973.1, ECO:0000313|Proteomes:UP000033747};
RN [1] {ECO:0000313|EMBL:KJZ15973.1, ECO:0000313|Proteomes:UP000033747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S3726 {ECO:0000313|EMBL:KJZ15973.1,
RC ECO:0000313|Proteomes:UP000033747};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJZ15973.1}.
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DR EMBL; JXYC01000004; KJZ15973.1; -; Genomic_DNA.
DR RefSeq; WP_046015688.1; NZ_JXYC01000004.1.
DR AlphaFoldDB; A0A0F4R7S3; -.
DR PATRIC; fig|579484.3.peg.735; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000033747; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033747};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 284..575
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 640 AA; 71554 MW; 681ACFEE0D814098 CRC64;
MKSVFNYIFN LSRPIKRIIT LLLDAFFIFS AFWGAWIVRV DNPDVFFSKE NWVLFFFVLS
ATLLVFIHLG LYLSVLRYIG NKVVVSVLTG CSISVLSLVL LTFYLGYELP RSIPLIYFTF
LILFIGGSRF SIRLITMHTS KRDKTRVVVY GSGPAGRQLA QLLMHGKEFD PVAFIDDDKN
LQNTFILGRP VYSFKHLVQL SKNVDISKVL LAMPNIGTIE RKKILTKLEP LALEVKSIPD
MSDLVSGDAK IDELRDVAID DLLGREAVEP RKDLLGKNIS NKVVMVTGAG GSIGSELCRQ
IIQNKPKILI LFELSEFALY TIHEELTKKL NDLDTTCEIK PIIGSVQDSD RIYSVLSNFS
VNTIYHAAAY KHVPLVEYNV IEGVKNNVFG TYYAATAALK AKVETFVLIS TDKAVRPTNI
MGTTKRVAEL VLQALNKKTS NTTFCMVRFG NVLGSSGSVV PLFKEQISKG GPVTITHKDI
TRYFMTIPEA SQLVIQAGAM AKGGEVFVLD MGESVKISDL AVKMIHLMGL EVKSDSNPFG
DIELQYSGLR PGEKLYEELL IGDNSSKTDH LRINKANEIS LEWDDMQALL DSLDLSAEKF
DVENVQRLLK DAPTGYLPTS KLCDLMFEEK RSEPHYNSLH
//
