ID A0A0F4Z886_9PEZI Unreviewed; 774 AA.
AC A0A0F4Z886;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=TD95_004741 {ECO:0000313|EMBL:KKA26707.1};
OS Thielaviopsis punctulata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Thielaviopsis.
OX NCBI_TaxID=72032 {ECO:0000313|EMBL:KKA26707.1, ECO:0000313|Proteomes:UP000033483};
RN [1] {ECO:0000313|EMBL:KKA26707.1, ECO:0000313|Proteomes:UP000033483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-DP1 {ECO:0000313|EMBL:KKA26707.1};
RA Radwan O., Al-Naeli F.A., Rendon G.A., Fields C.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKA26707.1}.
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DR EMBL; LAEV01002029; KKA26707.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F4Z886; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000033483; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000033483}.
FT DOMAIN 112..299
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 334..512
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 86747 MW; 8770D1648FEC6A4E CRC64;
MNPEPPRKKK KRSHDPNVIM AGGKPVSLAA LLDEPPKRKE PATKQLGPPV TATPEPTRSP
SPEPSNHKPR DKSNGKGYYG KNAPRDSRWK ENPVLLKTRQ KLPIWAYRNN IREALRRNDT
LVVVGETGSG KSTQIPQFLY TEPWCQRRKV RVPNLPDPVN VGGVIAVTQP RRVAATTLAH
RVAQEAGSPL GRPEGQVGYS VRFDHNVPRG TKIKFLTEGM LLQELLQDPH LRQYSAVIVD
EIHERSVDVD LLSGFLKKIR LEGTANRGGV PLKVIIMSAT ADVEEMKDFF SEEEPAADSE
KKQKKSAEVL HVKGRQFPVE LIHTPKPVAD LQDQLLKTVF KVHTEEPLPG DILAFMTGQE
DIEAAVKLID EYGATLASNM PKIKAFPLFG QMSMEAQHAA FQPLNEKFTR KVILATNIAE
TSVTVPGVRY VIDCGKAKVK QFRTRLGMES LLAKPISMSS AIQRAGRAGR EGPGKCFRMY
TEDGFNELEE RDLPEILRTD LMTAILTMKA YGIDDIQAFP LIDMPDVEAL EYALVQLCLL
GAIDKTGAIT EAGRKISKLP ISPPFGVVLL TSAKPEFDCV LEVIDIISCI TSGEDIFQHI
QTEEVREEVE EMRKQLFRRE GDLLTLLTTM QLYSSENADR TQWCQQRRIN MRNMRQAMKI
RKQLRGLALK MKLLTEPPQP DPQPFVPPSP DKADAILRCF LKGFMSRTAT LHADASYHTV
LGKQIVAIHP SSVLHGRKVE AIMFLENVFT QKNYAKKVSA VRADWLMEEW KHGM
//
