ID   A0A0F4ZIR5_9PEZI        Unreviewed;      1109 AA.
AC   A0A0F4ZIR5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   ORFNames=TD95_004374 {ECO:0000313|EMBL:KKA30427.1};
OS   Thielaviopsis punctulata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Ceratocystidaceae; Thielaviopsis.
OX   NCBI_TaxID=72032 {ECO:0000313|EMBL:KKA30427.1, ECO:0000313|Proteomes:UP000033483};
RN   [1] {ECO:0000313|EMBL:KKA30427.1, ECO:0000313|Proteomes:UP000033483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-DP1 {ECO:0000313|EMBL:KKA30427.1};
RA   Radwan O., Al-Naeli F.A., Rendon G.A., Fields C.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|RuleBase:RU367072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA30427.1}.
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DR   EMBL; LAEV01000389; KKA30427.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F4ZIR5; -.
DR   OrthoDB; 38995at2759; -.
DR   Proteomes; UP000033483; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF14500; MMS19_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|RuleBase:RU367072};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033483}.
FT   DOMAIN          65..327
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
SQ   SEQUENCE   1109 AA;  118461 MW;  9DBB9135D9A2931B CRC64;
     MADFDQLALK FVLEDEHPVR DALAAEAADA IKNAPRASNP VRRWVESVRP WILGDDADGS
     GSGSGDRIAR ARALDFLSTT LSLLDKDLLR QDQIKVLIAY FSSMFTIDHR SGILPSAKAL
     STLTHMKFFP VDAAANMLHS VCSMADDFRN QIPVTRLAVY DLFATCLSNS AIAADLRAKQ
     AADPILIREV LAMCHSERDP KNIMRWFGLL AVFLADFAPL PADVSQEIFA TFSAYFPISL
     RTSQHPSGIT AEDLKTALRK CFIASPEMAE HAFPFLLGKI EQGSGVTVNV KLDIIRTLEA
     GIKSYTPSST KVAPFADRIW SALKYEVRNG DVDETIDATL DLFTTLAKTL DDSHLQTFVL
     SVLRECTDDL SGSTYAAGAG KVLVALMRAK FSAFAPLVAP TVNHVRDTLR HSKSPEHSSA
     LLTLLNSTLA IRLLYLQRPE ALSADEQAAF KAVDPTFAAL YETTLKKLFA ETANTDPNKT
     AVQALGLLAS QPSALDPDAL LLSESTCRDI TVLLATLLVQ PALPNPVAQD TVEALQRIVV
     AWPPAFDILA DAAFSPERDT ADIPAMTALF SRVAFIACSG LPARTRSVYL TAVPLVARLV
     RGLVERVEAT QKNGDLAHPM WAVYITGLQA ALMHFADACK AHWPRAKTLG LPEGVSAESW
     VAYVEKTFPS VVPNGPTTTD IPDAQPSDTA HMDTLLLGLY AVRVFFQLTL TLSPSASVVL
     AAPFADSSDS SRRFLFFLGQ LTTHVIGQLT ETQQRLLALH DDVFLLFHSA ARGATYAHVQ
     APEHFVTDVS AETYAPLVAP ACLSLSTAVL HALYPSVVAA LFATGAGQTA VAHALTTTST
     PADPAVLAYW LTVLANKHTF ETTPLLHSLL CARLAALHTS PAGAPAAFGL LAGALRRYTG
     TSLSSPLAAL ALLPAAQPAL PVFFDYLFAP KPLLTAALHC TTKPTWSQRA YLAVLAPLLP
     GVPAGPATLA LLSAAQHLSF SVVRDDAPAL VRCALAALAA LPAAQAAGPG LAVLQHIMAA
     SPDLIETHAR SAIDACLRVA ADSDKSVPAA ARRSALVLVS AMPEKFDHRH LVAVAPRVKR
     ALAVASGDRV RGVRGVATKA RMTWATVDA
//