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Database: UniProt
Entry: A0A0F5F0L4_AVIPA
LinkDB: A0A0F5F0L4_AVIPA
Original site: A0A0F5F0L4_AVIPA 
ID   A0A0F5F0L4_AVIPA        Unreviewed;       456 AA.
AC   A0A0F5F0L4;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   05-JUL-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KKB02439.1};
GN   ORFNames=Z012_01270 {ECO:0000313|EMBL:KKB02439.1};
OS   Avibacterium paragallinarum (Haemophilus gallinarum).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Avibacterium.
OX   NCBI_TaxID=728 {ECO:0000313|EMBL:KKB02439.1, ECO:0000313|Proteomes:UP000033614};
RN   [1] {ECO:0000313|EMBL:KKB02439.1, ECO:0000313|Proteomes:UP000033614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL {ECO:0000313|EMBL:KKB02439.1,
RC   ECO:0000313|Proteomes:UP000033614};
RA   Horta-Valerdi G., Sanchez-Alonso P., Negrete-Abascal E., Perez V.,
RA   Olmedo G., Hernandez I., Gomez Z., Vazquez-Cruz C.;
RT   "Sequence of Avibacterium paragallinarum strain CL genome contains
RT   many ISs.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKB02439.1}.
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DR   EMBL; LAEN01000005; KKB02439.1; -; Genomic_DNA.
DR   RefSeq; WP_046097689.1; NZ_LAEN01000005.1.
DR   EnsemblBacteria; KKB02439; KKB02439; Z012_01270.
DR   PATRIC; fig|728.38.peg.1723; -.
DR   Proteomes; UP000033614; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033614};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033614}.
FT   DOMAIN      153    284       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      364    433       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     161    168       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   456 AA;  51881 MW;  664CEE49B827C0C4 CRC64;
     MKMTLTSLWQ DCLSQLQDQV SPTDFSTWLR PLQADIPSEN QMVLYASNVF VKNWVETHYL
     ELITKLSQSL SGNIDFSVRV QEGTKPAKLV EKKNVVPPHS PMQTESTAKT EAKQPYRSNL
     NTKHIFENFV EGKSNQLARA VAQKVAINPG EQSANPLFLY GGTGLGKTHL LHAVGNGILA
     SKPDARVIYI HAERFMQEYV KALQADKMEN FKKFYRTLDA LLIDDIQFFA GKDGTQEEFF
     HIFNSLFESS RQIILTSDRY PKEIEKIEDR LKSRFGWGLS VAIEPPELET RVAILLKKAE
     EKQMLLPEEV AFFIGQKLRT NVRELEGALN RVHANAEFTG KAITIDFVRE TLKDMLALQD
     KLVTVENIQK VVAEYYRIKV ADLKSKNRSR SVARPRQLAM ALSKELTNRS LPEIGKAFGD
     RDHTTVLHAC RTIATLREQD NNIQEDWSNL IRTLSA
//
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