ID A0A0F5MQ16_9RICK Unreviewed; 322 AA.
AC A0A0F5MQ16;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Arabinose 5-phosphate isomerase KdsD {ECO:0000313|EMBL:KKB96746.1};
DE EC=5.3.1.13 {ECO:0000313|EMBL:KKB96746.1};
GN Name=kdsD {ECO:0000313|EMBL:KKB96746.1};
GN ORFNames=SZ25_00180 {ECO:0000313|EMBL:KKB96746.1};
OS Candidatus Arcanobacter lacustris.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales; Arcanobacter.
OX NCBI_TaxID=1607817 {ECO:0000313|EMBL:KKB96746.1, ECO:0000313|Proteomes:UP000033358};
RN [1] {ECO:0000313|EMBL:KKB96746.1, ECO:0000313|Proteomes:UP000033358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC AAA041-L04 {ECO:0000313|EMBL:KKB96746.1,
RC ECO:0000313|Proteomes:UP000033358};
RA Martijn J., Schulz F., Zaremba-Niedzwiedzka K., Viklund J.,
RA Stepanauskas R., Andersson S.G.E., Horn M., Guy L., Ettema T.J.G.;
RT "Single cell genomics of a rare environmental alphaproteobacterium provides
RT unique insights into Rickettsiaceae evolution.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SIS family. GutQ/KpsF subfamily.
CC {ECO:0000256|ARBA:ARBA00008165, ECO:0000256|PIRNR:PIRNR004692}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKB96746.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYHA01000028; KKB96746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F5MQ16; -.
DR PATRIC; fig|1607817.3.peg.181; -.
DR Proteomes; UP000033358; Unassembled WGS sequence.
DR GO; GO:0019146; F:arabinose-5-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd04604; CBS_pair_SIS_assoc; 1.
DR CDD; cd05014; SIS_Kpsf; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR004800; KdsD/KpsF-type.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035474; SIS_Kpsf.
DR NCBIfam; TIGR00393; kpsF; 1.
DR PANTHER; PTHR42745; -; 1.
DR PANTHER; PTHR42745:SF1; ARABINOSE 5-PHOSPHATE ISOMERASE KDSD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01380; SIS; 1.
DR PIRSF; PIRSF004692; KdsD_KpsF; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Isomerase {ECO:0000313|EMBL:KKB96746.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR004692-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000033358};
KW Zinc {ECO:0000256|PIRSR:PIRSR004692-2}.
FT DOMAIN 40..181
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 271..322
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT BINDING 80
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-2"
FT SITE 57
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 109
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 150
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 190
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
SQ SEQUENCE 322 AA; 34592 MW; 8EFDC31E486523D0 CRC64;
MNKKMIVSVD VEIAKQVINT EIEGLQSLSQ ALDYSFVELV ETIFLLKGKV ILSGIGKSGI
IAKKIASTLA STGTPSFFVH PSEASHGDLG MITRDDLVFL LSNSGETQEI RDLVSYCKKI
DIKLVALVGN SNSQLANAAD IKIILPQIKE ASDLQSPTTS TTMMIVFGDA LAVTLLEKRG
FNKEDYKLLH PGGKIGSIFT KVKDLMHKDD AIPLVGSSSL MSDAIMTMSL KRLGCVGVID
SAGGLMGIIC DGDLRRNMGP NLLGTSVLEI MNKNPKTIDS ESLAVDAANL MNENGITTLF
ITEQNKPMGI IHIHDCLKVG KN
//
