ID A0A0F5VTW1_9ACTN Unreviewed; 339 AA.
AC A0A0F5VTW1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KKD05624.1};
GN ORFNames=TN53_22980 {ECO:0000313|EMBL:KKD05624.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD05624.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD05624.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD05624.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD05624.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXTE01000038; KKD05624.1; -; Genomic_DNA.
DR RefSeq; WP_046260493.1; NZ_JXTE01000038.1.
DR AlphaFoldDB; A0A0F5VTW1; -.
DR PATRIC; fig|1415558.3.peg.4709; -.
DR OrthoDB; 3510266at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 339 AA; 36269 MW; 5CC3F1D9EC2D464E CRC64;
MTVSITDVAR AAGVSASTVS RALRGQPGVS DEVRAQITTV AAQLGYTASR SASSLASGRT
YTIGVVVPYI GRWFFGTVLD AAEKVFSAAG YDVLLYNLNS PEARKRFFTK LPVRKRVDAV
LSLLIPDLEE ESALRSLGVP LATTVGGPRD GFTVVGIDDH TGATSAVRHL VNLGHRRIGM
ISGASEPLHW TTPIDRRQAY LDVLAEAGIA HDPALEADGG YTVDGGERAM TEILAVSRPP
TAVFAQSDEM AMGALRALRR HRLKVPDDVS VVGFDDHELA EVIGLTTVAQ PVPEQGAEAA
RLLLRRLDEP DAEPVGQVRM PIRLMLRETT APPSPHRPS
//
