ID A0A0F5VW73_9ACTN Unreviewed; 347 AA.
AC A0A0F5VW73;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KKD06042.1};
GN ORFNames=TN53_21345 {ECO:0000313|EMBL:KKD06042.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD06042.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD06042.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD06042.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD06042.1}.
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DR EMBL; JXTE01000033; KKD06042.1; -; Genomic_DNA.
DR RefSeq; WP_046260176.1; NZ_JXTE01000033.1.
DR AlphaFoldDB; A0A0F5VW73; -.
DR PATRIC; fig|1415558.3.peg.4300; -.
DR OrthoDB; 3227375at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06296; PBP1_CatR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..67
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 322..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 37396 MW; 849EE3A96C4882C0 CRC64;
MVRTGSASVA AGPTLAVVAR EAGVSVPTAS KVVNGREDVA PETRRRVTEA LDRLGYVRRP
RFDAAKPPAL VDLVVHSLNS SWSGAVLHGV EEAAHDAGLE VVVSAGLTRQ RCGRPERGWL
DKLIARGSSG VLFNLAELTP SQYAWLEQHR IPFVMIDPVV EPPAGVVSVG AANWQGGMAA
TEHLLALGHE RIAVIAGTRR KMCSTARVAG YRSALASAGV RQRPEYVRHA SFDESVARER
MRELLDLPEP PTAVFVCSDR MALGVYEALA ERGLSIPDDM SVVGFDDLPE ARWASPALTT
VRQPLSEMAA TATRLLVRMM EGTRPEGTRT ELSTRLVERA STGRPRG
//
