ID A0A0F5VZ14_9ACTN Unreviewed; 313 AA.
AC A0A0F5VZ14;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=RNA methyltransferase {ECO:0000313|EMBL:KKD07368.1};
GN ORFNames=TN53_14020 {ECO:0000313|EMBL:KKD07368.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD07368.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD07368.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD07368.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD07368.1}.
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DR EMBL; JXTE01000018; KKD07368.1; -; Genomic_DNA.
DR RefSeq; WP_046258777.1; NZ_JXTE01000018.1.
DR AlphaFoldDB; A0A0F5VZ14; -.
DR PATRIC; fig|1415558.3.peg.2128; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:KKD07368.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transferase {ECO:0000313|EMBL:KKD07368.1}.
FT DOMAIN 71..148
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 32888 MW; 7CDC27A93D265167 CRC64;
MAANNRRMSG KKGAQVGSGG QRRKGLEGKG PTPPAEMRKK HKANRIANAK AKQAARRPTP
RGRGGKGTSE MVVGRNPVVE ALREGVPAMT LYVQQFIDND ERVREALQLV AERGGINLME
APRPELDRMT NGLNHQGLVL QVPPYEYAHP EDLANAAYDH GEDPLIVALD GVTDPRNLGA
VVRSVSAFGG HGVVVPERRA AGMTAGAWKT SAGTAARTPV ARATNLTRAL EAYQKAGIAV
VGLAADGEHE IGDLEALGGP VVIVVGSEGK GLSRLVGETC DFRVRIPMPG GAESLNAGVA
AGVVLYEAAR RRA
//
