ID A0A0F5ZZY9_9GAMM Unreviewed; 392 AA.
AC A0A0F5ZZY9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Hemolysin {ECO:0000313|EMBL:KKD61268.1};
GN ORFNames=RN22_06565 {ECO:0000313|EMBL:KKD61268.1};
OS Grimontia sp. AD028.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Grimontia.
OX NCBI_TaxID=1581149 {ECO:0000313|EMBL:KKD61268.1, ECO:0000313|Proteomes:UP000033732};
RN [1] {ECO:0000313|EMBL:KKD61268.1, ECO:0000313|Proteomes:UP000033732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AD028 {ECO:0000313|EMBL:KKD61268.1,
RC ECO:0000313|Proteomes:UP000033732};
RA Adrian T.-G.-S., Chan K.-G.;
RT "Genome sequencing of Grimontia sp. AD028.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD61268.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LASY01000027; KKD61268.1; -; Genomic_DNA.
DR RefSeq; WP_046303613.1; NZ_LASY01000027.1.
DR AlphaFoldDB; A0A0F5ZZY9; -.
DR PATRIC; fig|1581149.3.peg.1867; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000033732; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF4; UPF0053 PROTEIN SLL1254; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..178
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 262..320
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 343..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 43426 MW; 1943A07E31822943 CRC64;
MILLFMFVAL SIGVSFICSV LEAVLLSITP SYLAQMRQQG HPAAGRLSSL KDDIDRPLAS
ILTLNTIAHT VGAAASGAQA AKVFGDAWLG VFSGVLTLAI LVLSEIVPKT IGATYWRQLA
PGAATVLRWM VWALTPFVWA SEQLTRRLAR GKEQPKLRDE ISAMAMLAKE SGELEDDEST
MLTNLLSLRD VPVTKLMTPR PVLFRVDATM TIEDFLREHH DTPFSRPLVY AESRDNILGF
VHRLELFSAS QHGKGQKQLG SLMRPIPVVH DSTIVPKAFD RLMAQRSQLA LIVDEYGDVQ
GIITLEDIFE HLMGKEIMDE ADKTSNMQAL AHERWEDWKE AHGVIESKDD DEEEADKAAE
ELAEASEKEE ASQKNTEDGK ATSLNDEEKT SK
//
