ID A0A0F6A4R1_9GAMM Unreviewed; 223 AA.
AC A0A0F6A4R1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=N479_23345 {ECO:0000313|EMBL:KKE81220.1};
OS Pseudoalteromonas luteoviolacea S4054.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=1129367 {ECO:0000313|EMBL:KKE81220.1, ECO:0000313|Proteomes:UP000033434};
RN [1] {ECO:0000313|EMBL:KKE81220.1, ECO:0000313|Proteomes:UP000033434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4054 {ECO:0000313|EMBL:KKE81220.1,
RC ECO:0000313|Proteomes:UP000033434};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKE81220.1}.
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DR EMBL; AUXW01000191; KKE81220.1; -; Genomic_DNA.
DR RefSeq; WP_046358281.1; NZ_AUXW01000191.1.
DR AlphaFoldDB; A0A0F6A4R1; -.
DR PATRIC; fig|1129367.4.peg.4981; -.
DR Proteomes; UP000033434; Unassembled WGS sequence.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 27..219
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 223 AA; 23883 MW; 73958AC953B8537E CRC64;
MKKVLIPVTN HATLGNTDQP NGTYAPELTH VVAVLNAHQI EFDIVSLKGG KAPLYGTDIE
GDHVNSDILA DAAFIQKVDN TQRIAEVNID EYGAIFYPGG FGLLSDLATD KTMAALAAKH
YETGGVISAV CHGPAALLPI TLSSGNALIS DKKVTSFTRE EEVDFGTIDD IPFLLEESLT
RTASQFHKVQ PWQSFTVVDE RVITGQNPAS AHAVGELLVS QLV
//
