ID   A0A0F6AFF9_9GAMM        Unreviewed;       883 AA.
AC   A0A0F6AFF9;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=N479_07570 {ECO:0000313|EMBL:KKE84947.1};
OS   Pseudoalteromonas luteoviolacea S4054.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=1129367 {ECO:0000313|EMBL:KKE84947.1, ECO:0000313|Proteomes:UP000033434};
RN   [1] {ECO:0000313|EMBL:KKE84947.1, ECO:0000313|Proteomes:UP000033434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S4054 {ECO:0000313|EMBL:KKE84947.1,
RC   ECO:0000313|Proteomes:UP000033434};
RX   PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA   Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT   "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT   bacteria.";
RL   BMC Genomics 16:158-158(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKE84947.1}.
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DR   EMBL; AUXW01000090; KKE84947.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F6AFF9; -.
DR   PATRIC; fig|1129367.4.peg.1154; -.
DR   Proteomes; UP000033434; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13426; PAS_9; 3.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        183..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          324..370
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          397..449
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          481..614
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          623..875
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   883 AA;  99164 MW;  CBC01F31A19CB343 CRC64;
     MRVDGVLGGG GLKTITKIAQ RLLFACIGLH ATQTLAQTLP TEVFDNHSAV MLLIEPDSGK
     IVRANQAAAD FYGYNKAQLQ ALYIQEINQF SPQQVEKERL SALNEGRNYF IFQHRLANGE
     NRTVSVYSSP FMASNGEALL FSVIQDVSER RKLEHALWHY QSNLEQQVAQ QTREIKHAST
     VQVFLLSSVI GIFVGTTVIL GWGFLRLRKT KKRSEFHRAR LNAIFDAIGD YLIFTDVNDK
     VLSANRSAYQ DLGELDNKAI VDVLSKCVCL EQLQFEPKEC QIKTNFGTLD VEISKTDVLD
     HNGGLYGHIF LLQNITQRLA DEKEQRLAST VFSTTSEGVL VSDKDNCIQM VNRAFTDITG
     FSGPEVMGKT PAIFNSGRHD TAYFTQLYDA LSTRGHWEGE IWNKRKNGEV YPSWLQVSAV
     FDQHGDIDMY VALFNDITSR KRNEQLMWQQ ANFDNLTDLA NRHHYHAKFD IALAQAQRKQ
     TRVAVCFIDL DRFKAVNDTL GHHIGDLLLI EAANRIRECT RNSDTVARLG GDEFALLLPD
     MDLISDMEKL ADKVLTALSA PFHLEGHEAY VSGSMGITFY PDDGEDRKVL LRNADSAMYK
     AKESGRNCYQ FFTTAMHEHA KARSQLEGAL HRALANQELR VVYQPIVGDE QRLGCEALLR
     WHNEVLGDVS PADFIPISEE LGLIISMGEW VLYQACAQAR AWLTKTQRPF FVSVNVSSIQ
     FKRQNVVALV AKVLKDTGLP AESLTLEITE TVLADNSDDI ERQLEQLRAM GVGLAIDDFG
     TGYSSLGYLK RFPLSKLKID RAFIKDLPDD EEDKTLISAI ISMASKLKLT VIAEGVETEA
     QLDLLQELGC DYTQGYLHAK PCSASEFEVF LQQYHDASTH SQI
//