ID A0A0F6TCW1_9CORY Unreviewed; 422 AA.
AC A0A0F6TCW1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Precorrin-6Y C5,15-methyltransferase (Decarboxylating) {ECO:0000313|EMBL:AKE41204.1};
DE EC=2.1.1.132 {ECO:0000313|EMBL:AKE41204.1};
GN Name=cbiE {ECO:0000313|EMBL:AKE41204.1};
GN ORFNames=UL82_05140 {ECO:0000313|EMBL:AKE41204.1};
OS Corynebacterium kutscheri.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=35755 {ECO:0000313|EMBL:AKE41204.1, ECO:0000313|Proteomes:UP000033457};
RN [1] {ECO:0000313|EMBL:AKE41204.1, ECO:0000313|Proteomes:UP000033457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20755 {ECO:0000313|EMBL:AKE41204.1,
RC ECO:0000313|Proteomes:UP000033457};
RX PubMed=26021937;
RA Ruckert C., Albersmeier A., Winkler A., Tauch A.;
RT "Complete Genome Sequence of Corynebacterium kutscheri DSM 20755, a
RT Corynebacterial Type Strain with Remarkably Low G+C Content of Chromosomal
RT DNA.";
RL Genome Announc. 3:e00571-15(2015).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; CP011312; AKE41204.1; -; Genomic_DNA.
DR RefSeq; WP_046439368.1; NZ_LR134407.1.
DR AlphaFoldDB; A0A0F6TCW1; -.
DR STRING; 35755.UL82_05140; -.
DR KEGG; cku:UL82_05140; -.
DR HOGENOM; CLU_031955_0_0_11; -.
DR OrthoDB; 9787825at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000033457; Chromosome.
DR GO; GO:0046025; F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AKE41204.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033457};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AKE41204.1}.
FT DOMAIN 24..210
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 422 AA; 45353 MW; C41821BE8F114995 CRC64;
MNNPARTDAL HLAQGRDGEH KTQVSVVGIG AGGFAELGRS AQKVLLEAAV IIGSWRQLGL
LPDHISGLRH PWPSPMLPSI PEIFANFQGQ RIVVLGSGDP MFHGIGTTLR KVLPQLDFNV
YPQPSSASLA CARLGWALDR TPVESLVTNE VNTLLLRIQE GNRFLVLGRD ENSPQQICDF
LVTAGQPQAI IEVLNDLGGV DESYTQGTAA QPPSVVSSLN VIAISHLLPP TLSRVPGLND
DLFTNDGQLT KQHIRALTVS ALRPKEGETL WDIGGGAGSI AIEFLRATQT SHAVCFEQEP
SRQQRILDNA LQLGVAHRLA VQASAPDNYT CVPDNPDVIF IGGGLTAPGV FDGAWQRLND
GGRLVANAVT IESEQKLIEL RRQLGGSLSR FAMSHERGVG SFSAFQSAFP VTQWSIIKEA
NS
//
