ID A0A0F7HHW4_9STAP Unreviewed; 211 AA.
AC A0A0F7HHW4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Kynurenine formamidase {ECO:0000256|ARBA:ARBA00014889};
DE EC=3.5.1.9 {ECO:0000256|ARBA:ARBA00012930};
GN ORFNames=AAT16_01790 {ECO:0000313|EMBL:AKG73064.1};
OS Salinicoccus halodurans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Salinicoccus.
OX NCBI_TaxID=407035 {ECO:0000313|EMBL:AKG73064.1, ECO:0000313|Proteomes:UP000034029};
RN [1] {ECO:0000313|EMBL:AKG73064.1, ECO:0000313|Proteomes:UP000034029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H3B36 {ECO:0000313|EMBL:AKG73064.1,
RC ECO:0000313|Proteomes:UP000034029};
RX PubMed=26634017;
RA Jiang K., Xue Y., Ma Y.;
RT "Complete genome sequence of Salinicoccus halodurans H3B36, isolated from
RT the Qaidam Basin in China.";
RL Stand. Genomic Sci. 10:116-116(2015).
RN [2] {ECO:0000313|Proteomes:UP000034029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H3B36 {ECO:0000313|Proteomes:UP000034029};
RA Ma Y., Jiang K., Xue Y.;
RT "Complete genome sequence of Salinicoccus halodurans strain H3B36, isolated
RT from the Qaidam basin of China.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-
CC kynurenine, the second step in the kynurenine pathway of tryptophan
CC degradation. {ECO:0000256|ARBA:ARBA00002204}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + N-formyl-L-kynurenine = formate + H(+) + L-kynurenine;
CC Xref=Rhea:RHEA:13009, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:15740, ChEBI:CHEBI:57959, ChEBI:CHEBI:58629; EC=3.5.1.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000640};
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DR EMBL; CP011366; AKG73064.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F7HHW4; -.
DR STRING; 407035.AAT16_01790; -.
DR KEGG; shv:AAT16_01790; -.
DR PATRIC; fig|407035.3.peg.379; -.
DR Proteomes; UP000034029; Chromosome.
DR GO; GO:0004061; F:arylformamidase activity; IEA:UniProtKB-EC.
DR GO; GO:0004328; F:formamidase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:InterPro.
DR Gene3D; 3.50.30.50; Putative cyclase; 1.
DR InterPro; IPR007325; KFase/CYL.
DR InterPro; IPR037175; KFase_sf.
DR InterPro; IPR017484; Kynurenine_formamidase_bac.
DR NCBIfam; TIGR03035; trp_arylform; 1.
DR PANTHER; PTHR31118; CYCLASE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR31118:SF32; KYNURENINE FORMAMIDASE; 1.
DR Pfam; PF04199; Cyclase; 1.
DR SUPFAM; SSF102198; Putative cyclase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Tryptophan catabolism {ECO:0000256|ARBA:ARBA00023079};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
SQ SEQUENCE 211 AA; 23314 MW; E96270A00F57F6AA CRC64;
MMWMDITQTL DHSIAHWPED TPFSYEIPVT KAQSGSVNIG KIETSTHIGT HIDAPFHFND
EGLKVDELDI NRYIGDATVI EVMDQALITE EALKSFSIKG TILLIKTKEQ ANQDIFPETV
PVLSEKAVEH IAKIGIKLFG IDVTSVDPVD SKTLDIHHKL HRNDIMIIEN AVLGDVTAGY
YDFIALPLKI KGADGSPVRA ALRRQGGISN E
//
