ID A0A0F8AG36_LARCR Unreviewed; 890 AA.
AC A0A0F8AG36;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA replication licensing factor MCM2 {ECO:0000256|ARBA:ARBA00018925};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=D5F01_LYC03291 {ECO:0000313|EMBL:KAE8298786.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KAE8298786.1, ECO:0000313|Proteomes:UP000424527};
RN [1] {ECO:0000313|EMBL:KAE8298786.1, ECO:0000313|Proteomes:UP000424527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMULYC20181020 {ECO:0000313|EMBL:KAE8298786.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAE8298786.1};
RA Xiao S.;
RT "Chromosome genome assembly for large yellow croaker.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8298786.1}.
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DR EMBL; REGW02000003; KAE8298786.1; -; Genomic_DNA.
DR RefSeq; XP_019128234.1; XM_019272689.1.
DR AlphaFoldDB; A0A0F8AG36; -.
DR GeneID; 104931987; -.
DR KEGG; lco:104931987; -.
DR CTD; 4171; -.
DR eggNOG; KOG0477; Eukaryota.
DR OrthoDB; 5476523at2759; -.
DR Proteomes; UP000424527; Unassembled WGS sequence.
DR GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR CDD; cd17753; MCM2; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR008045; MCM2.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF44; DNA REPLICATION LICENSING FACTOR MCM2; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF12619; MCM2_N; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR PRINTS; PR01658; MCMPROTEIN2.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000424527};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 890 AA; 100002 MW; 807FFDF589A03E40 CRC64;
MADSSESYHM ATSPSRASRR GDMTSSPGRD LPPFEDESEG LLGDGQLPGE EEEDGDGEEL
IGDGMERDYR AIPALDQYEA EGLDLDDEDL SELSPGARAA AEEAMRRRDR EQGVSGRLRR
GLLYDSEDED DERPAARRRR LAERAAEGVA DGEEEEMIES IENLEDMKGH TVREWVSMTA
PRLEIYNRFK NFLRTHVDEN GHNVFKEKIS DMCKDNKESL VVNYEDLAAR EHVLAYFLPE
APTEMLKIFD EAAKEVVLAM YPKYERIAHE IHVRICNLPL VEEIRSLRQL HLNQLIRTSG
VVSSCTGVLP QLGMVKYNCN KCNFVLGPFF QSQNQEVKPG SCPECQSLGP FEINMEETVY
QNYQRIALQE SPGKVAAGRL PRSKDAILLA DLVDSCKPGD EIELTGIYHN NYDGSLNMAN
GFPVFATVIL ANHITRRDEG VAVAELTDED VKAINALSKD ERIGERIFAS MAPSIYGHED
IKRALALSLF GGEPKNPGGK HKVRGDINVL LCGDPGTAKS QFLKYAEKVA SRAVFTTGQG
ASAVGLTAYV QRHPVSREWT LEAGALVLAD RGVCLIDEFD KMNDADRTSI HEAMEQQSIS
ISKAGIVTSL QARCTVIAAS NPIGGRYDPS LTFADNVDLT EPIVSRFDVL CVVRDTVDPV
QDEMLARFVV GSHIKHHPSN KEGGVALEEM ILPNTSDVPP IPQDILRKYI IYAKERVHPK
LNQMDQDKVA RIYSDLRKES MATGSIPITV RHIESMIRMA EAHAKMHLRD YVLEDDVNMA
IRVMLESFID TQKFSVMRTM RKTFARYLAF RRDNNELLLF ILKQLVAEQV AYQRNRYGVQ
NDTIEIAEKD LHDKARQINI HNLTAFYDSD LFRSNKFSHD GKKKLILQQF
//
