ID A0A0F8AVJ7_9EURY Unreviewed; 715 AA.
AC A0A0F8AVJ7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:KKF39846.1};
GN ORFNames=FK85_25340 {ECO:0000313|EMBL:KKF39846.1};
OS Halorubrum saccharovorum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=2248 {ECO:0000313|EMBL:KKF39846.1, ECO:0000313|Proteomes:UP000053331};
RN [1] {ECO:0000313|EMBL:KKF39846.1, ECO:0000313|Proteomes:UP000053331}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H3 {ECO:0000313|EMBL:KKF39846.1,
RC ECO:0000313|Proteomes:UP000053331};
RA Rozanov A.S., Kotenko A.V., Bryanskaya A.V., Malup T.K., Peltek S.E.;
RT "Full genome sequence of Halorubrum H3 strain isolated from Burlinskoye
RT Salt Lake (Altai Krai, Russia).";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF39846.1}.
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DR EMBL; JNFH02000014; KKF39846.1; -; Genomic_DNA.
DR RefSeq; WP_050024109.1; NZ_JNFH02000014.1.
DR AlphaFoldDB; A0A0F8AVJ7; -.
DR OrthoDB; 23466at2157; -.
DR Proteomes; UP000053331; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR NCBIfam; NF041323; Nitr_red_NasA_Halo; 1.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053331}.
FT DOMAIN 2..60
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 567..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 76399 MW; 3AA3E9D4B2F358CC CRC64;
MSEWTPTTCM RCAVGCGHLQ QGYTNNYGLD TVRGDASHPV NRGLACQRGI NETADPNGEW
LTRPLIREDG NLIPTSWETA IGTVVSRIED ALAETRDGVA VLGSGQQTNE AAYALGKLAR
GGFGTRYYDA NTTLCMASAV QAYMQGFGSD APPPTYEDVP DAETHVIWGA NPKIAHPVLY
RWIADSASDD DSELIVVDPV ESETAADADL HVRPEPGTDL ALARAVLARA VEDGLVDREF
VEHHTEGFEA MVGSLPDISV AAETAGVSVE RVSELAAAFD ARTLVYWGMG VNQSVQGTGT
ARSLIDLCLA TGNLGPGSGP FSLTGQANSM GNRVCASKSS WPGYRPFDDV DHRKTIAREW
GVPLSRLPDS SGPGFVRIID ELARDNIDVC WTVATNPVAG MPDANHVESA LDDTFLIAQD
AFRSDTVELA DVVLPAATWG ESEGTVMNME RRVSRVTAAR EPPDGVRQDV DIIGAVADRI
VPDLFESTRL DPEALFDELS ALTRGTTADL SGISYERLSE ELAVRWPAPD ETGEGGYRYY
VGDGGETTAN DADSPWSFPT DSGRARFSNT SHRGVPEPID TEYPLTLTTG RRPDVYNTGV
RTRSDAGDGD ESATAARMHP ETIADHLRAF DRGETVIESR RSAVTVSVTP DADVPPGLVW
LPVHNPAANE LTLSAADPES AEPNLKQCAI SLSAPDRTST DLTGSGKANG TSSYS
//
