ID A0A0F8DLY2_CERFI Unreviewed; 1237 AA.
AC A0A0F8DLY2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=CFO_g764 {ECO:0000313|EMBL:KKF96879.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF96879.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF96879.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF96879.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF96879.1}.
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DR EMBL; LBBL01000025; KKF96879.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8DLY2; -.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17982; DEXHc_DHX37; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF99; ATP-DEPENDENT RNA HELICASE DHX37-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:KKF96879.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KKF96879.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841}.
FT DOMAIN 413..592
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 614..854
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 120..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..318
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..717
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1237 AA; 137043 MW; 1C8F6E755C50E7E4 CRC64;
MPKFVPRQRK HKVLAREKAA ANAVHTYDPN AEELTPLDAA KKRELAEAKA ALLVKGTKVS
SKKAKRLEKY IEKKLRKDES RMLIQKLGES KIDTSLFAKT SAIGQAKETK RQTLQRALQE
EKAGIQNGDS KTILYQEREE VDVSEAPEVK KVLESDEPTR KRKKSKGRGG KPNTEEEEDK
EMVDAKPESD PEATCEDIPE VPETAPAVVS VGSGLKRPLE TDDDGRPVLK KRQKRGGVAT
KHSLIYAKPQ VVEENEDDDE FEGFDDEDDE SDSLEEGSEI EEDDEEDDDE EDDEEGEEED
SSDEEEDEDS DDGDSSEIDQ EENKQRSSSF RAWALQQRNE ALGFKPSTEA SYLEFPTVQG
FVPRAPESDP LPRELQPTTN LERKVYSVTV SRPEAIQEAR MKLPVVAEEQ RIMEAIHNND
IVVVCGATGS GKTTQIPQFL FESGYGSPES PTPGMIGITQ PRRVAAVSMA KRVGEELAEY
GARVGYQIRF DGTVDSKTAV KFMTDGVLLR EVAQDITLAK YSAIVVDEAH ERSVNTDILV
GMLSRVAKLR RELADEDKTG ATKPLKLVIM SATLRVDDLI KNPVLFPTPP PVLEVEGRQH
PVTLHFSRRT HADYVEEAFK KVSRAHRKLP PGGILVFLTG QNEIAELSKK LKAQFDSGAS
SGSAPKVKVL ASEAVLEAED IDLGDADMSE MIDDMVYDSE DEEGEDGDED EFKIEDDDED
APPKMKVLPL YSLLPTREQL RVFEPVPEGT RLVILATNVA ETSLTIPGIR YVFDTGRAKE
RRFDRLSGVQ SFDIGWISKA SASQRAGRAG RTGPGHCYRL YSSAVFERDF DAFSQPEILR
MPIEGVVLQL KAMKLHNVVN FPFPTAPSRP MLAQAERLLE YLSALTAEGS KITPLGTTMS
MFPLSPRFAR ILLVGHLHDC MPYTISMIAA LSVGDVFIPE SHVVPQEPEA NADGVVFNDG
RDDERTALRK KFNAAHHRFC HLDERSDAIK LLQVLGEFAH VPTEAWARDH FVRYKALAEA
TQLRKQIVSL LQKYIPAFAN LRVADKLPPP SEKQVTALKQ MVAVGFVDQI AIRADLSPTP
PEMRRKPRRA IDVPYVPLVP LNDGPSGANN ADPLDSMVYL HPSSPMAHLS VAECPEYVVY
GHLQRGAAVA IGSDKMPKTR MHSLTDITGA QLATIAKGTP LLSWGKPVKE VGTPTATERE
VWVVPYLRAE GTGGQGWPLP IRKVKQKKVA GKGWVVL
//
