ID   A0A0F8WZP5_9EURO        Unreviewed;       622 AA.
AC   A0A0F8WZP5;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   03-MAY-2023, entry version 20.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=ARAM_007433 {ECO:0000313|EMBL:KKK22940.1};
OS   Aspergillus rambellii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=308745 {ECO:0000313|EMBL:KKK22940.1, ECO:0000313|Proteomes:UP000034291};
RN   [1] {ECO:0000313|EMBL:KKK22940.1, ECO:0000313|Proteomes:UP000034291}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRRC1468 {ECO:0000313|EMBL:KKK22940.1,
RC   ECO:0000313|Proteomes:UP000034291};
RA   Moore G.G., Beltz S.B., Mack B.M.;
RT   "Draft Genome Sequences of Two Closely-Related Aflatoxigenic Aspergillus
RT   Species Obtained from the Cote d'Ivoire.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKK22940.1}.
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DR   EMBL; JZBS01001393; KKK22940.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F8WZP5; -.
DR   STRING; 308745.A0A0F8WZP5; -.
DR   OrthoDB; 2085300at2759; -.
DR   Proteomes; UP000034291; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05188; MDR; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR45033; -; 1.
DR   PANTHER; PTHR45033:SF3; DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034291};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        177..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..354
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   622 AA;  68752 MW;  78FDD44D5F4EE503 CRC64;
     MSKAIFLSKV EGKPGKVYYP LSLQTLPQPT PQGTELLVRM TAAALNHRDV FLRQHLYPGV
     TFDVPMGADG VGTVVGAGPG VLNPERWQGK RVILNPGVGW KDSPDGPEDP TGYKIMGGTK
     FYNKGTLQDY ITIEESELEE APEHLSDAEA AALPLAGLTG WRALVSKAGE KNSSKGAAIL
     ITGIGGGVAL STLLFAVARG ADVYVTSSSE EKLQKAIELG AKGGVNYKED GWEKKLLGML
     PGGKKNFDAI IDGAGGDSVE KANMDQTGGI LSVYGMTVSP VMPFTMTAVL KNIDVRGSTM
     GSRKEFKDMV EFVKSHKIHP VVSRTVQAEL SDVAALDGLF QDMKDSKQFG KLVFEFGKSS
     GTAFPDSRIV DNSRVMDMDT EIAQHYGPGM SFYLSHINSA RERADRKRSQ LMVGVLTADS
     GPWMRIDGIS FQQRKSHALT RFLQRYCATL RELYSTNQML HRKINQLCSD SLQLTRDMTK
     LNRHMGAFHG VILETCQADT LTRLIESIYE IHGWKFPGGL MLGEHVDLDR ETLSRIYTEA
     AKDVKKEMVT KKAVGLSEKY HVALQRYDQI VHHRSASPFR TECIFARWLG AKKSTHPGMY
     QFWERLFPVC YNRTVQESSE MF
//