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Database: UniProt
Entry: A0A0F9YVK5_9BACT
LinkDB: A0A0F9YVK5_9BACT
Original site: A0A0F9YVK5_9BACT 
ID   A0A0F9YVK5_9BACT        Unreviewed;       141 AA.
AC   A0A0F9YVK5;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Ferric uptake regulator, Fur family {ECO:0000313|EMBL:KKP30506.1};
GN   ORFNames=UR19_C0002G0027 {ECO:0000313|EMBL:KKP30506.1};
OS   Candidatus Nomurabacteria bacterium GW2011_GWF1_31_48.
OC   Bacteria; Candidatus Nomurabacteria.
OX   NCBI_TaxID=1618767 {ECO:0000313|EMBL:KKP30506.1, ECO:0000313|Proteomes:UP000034934};
RN   [1] {ECO:0000313|EMBL:KKP30506.1, ECO:0000313|Proteomes:UP000034934}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-2};
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-2};
CC       Note=Binds 1 Mn(2+) or Fe(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR602481-2};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-1};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR602481-1};
CC   -!- SIMILARITY: Belongs to the Fur family. {ECO:0000256|ARBA:ARBA00007957}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKP30506.1}.
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DR   EMBL; LBOG01000002; KKP30506.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F9YVK5; -.
DR   Proteomes; UP000034934; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1490.190; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR002481; FUR.
DR   InterPro; IPR043135; Fur_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33202:SF7; FERRIC UPTAKE REGULATION PROTEIN; 1.
DR   PANTHER; PTHR33202; ZINC UPTAKE REGULATION PROTEIN; 1.
DR   Pfam; PF01475; FUR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Iron {ECO:0000256|PIRSR:PIRSR602481-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR602481-1};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR602481-1}.
FT   BINDING         85
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-2"
FT   BINDING         91
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         94
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         127
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-2"
FT   BINDING         135
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         138
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
SQ   SEQUENCE   141 AA;  16622 MW;  01E3E29B698BDC13 CRC64;
     MIKDFSYLIK DKGFKVTQIR KDILGIFSND CKPINAEYIY KVLKNKKTNL VTIYRTLVSF
     EKEGILKRVD LHKESVYYEL VDDHHHHHII CLYCKKVYNF NGCKEDSDLL ISKALKQNKD
     FNSISHHSFD LFGICKKCSK K
//
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