ID A0A0F9ZJ86_9BACT Unreviewed; 453 AA.
AC A0A0F9ZJ86;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=methionine--tRNA ligase {ECO:0000256|ARBA:ARBA00012838};
DE EC=6.1.1.10 {ECO:0000256|ARBA:ARBA00012838};
DE AltName: Full=Methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030904};
GN ORFNames=UR35_C0011G0055 {ECO:0000313|EMBL:KKP44169.1};
OS Candidatus Woesebacteria bacterium GW2011_GWB1_33_22.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1618566 {ECO:0000313|EMBL:KKP44169.1, ECO:0000313|Proteomes:UP000034778};
RN [1] {ECO:0000313|EMBL:KKP44169.1, ECO:0000313|Proteomes:UP000034778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|RuleBase:RU363039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP44169.1}.
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DR EMBL; LBOW01000011; KKP44169.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9ZJ86; -.
DR STRING; 1618566.UR35_C0011G0055; -.
DR PATRIC; fig|1618566.3.peg.842; -.
DR Proteomes; UP000034778; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00814; MetRS_core; 1.
DR Gene3D; 2.170.220.10; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR InterPro; IPR023457; Met-tRNA_synth_2.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR033911; MetRS_core.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR PANTHER; PTHR43326:SF1; METHIONINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43326; METHIONYL-TRNA SYNTHETASE; 1.
DR Pfam; PF09334; tRNA-synt_1g; 1.
DR PRINTS; PR01041; TRNASYNTHMET.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363039};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363039};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363039}.
FT DOMAIN 5..344
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
SQ SEQUENCE 453 AA; 52255 MW; 47FD99506DE8629C CRC64;
MGRKFYITCA IPYVNAKPHV GHALEFVQGD VIARYHKLLG EDVILLSGGD ENALKNVQAA
EKANEPIQEF VDKNNKLFVE LTKNLNCEFD IWQKGSDKEK HFKSSQKLWE LCKDDIYQKE
YEGLYCVGCE AFYSPEDLNE NGECFEHPGK KLESVKEKNY FFKLSKYQKD LIDLISKDKL
KIYPIERRSN ERAKNWGVPV PNDDSQKIYV WFDALNIYQS GIGFGWDEEK YRKYWPADLH
IIGKGITRFH AVYWPAFLLS AGLKIPKALF VHGYFTVNGQ KMSKTLGNVI DPNEIIEKYG
ADALRYYFLA KFQPFTDGDF SESKLKDVYN ADLANGLGNL VSRVAKLCEN SKFEFKLSSP
EIYQQVSNSI KEFRFDNALK FIWEKITLVD KAVNKSEPWK LSGEILKETL QKYLCEIRTI
ALNLKPFLPN TSEKILANIG SNRPISEVLF PRL
//
