ID A0A0F9ZYY5_TRIHA Unreviewed; 649 AA.
AC A0A0F9ZYY5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 03-MAY-2023, entry version 21.
DE SubName: Full=MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:KKO98418.1};
GN ORFNames=THAR02_09475 {ECO:0000313|EMBL:KKO98418.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKO98418.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO98418.1}.
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DR EMBL; JOKZ01000422; KKO98418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9ZYY5; -.
DR OMA; AYCTDAF; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF3; PURINE TRANSPORTER; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 138..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 69959 MW; 46021673A412AE7F CRC64;
MESPTVQPKE GQESEAADPG IFSPRLPSPP AVGRSRFCGF RDFADLMDNW LSAGPLGRLF
HLAGSGHPDA IEGTSFFREI RAGLTTFATM AYIIAVNASV LSQTGGTCEC NLADKFQCDT
ISDFVDCKEE VRRDLITATA ALAGLSTLSF GLFTNLPVAL APGMGLNAYF AFQVVGYNGS
GAISYRTALT AVFFEGIIFM FLALTGMRQW LVRLIPATIK TATGVGIGFF LTEIGLSYTS
GIGAITGGGT ATPLSLGGCP PDMINAVTGA CNGGQMTNPT MWLAIFCGGI VTAFLMAFRV
KYALVIGIAL VSIISWPRNT PVTYFPNTPE GDSRFSFFKQ IVAWHPLSKT LNQLDWGFDT
ASTTHFVLGL FTFLYVDIID ATATLYSMVR FCGVVDPKDG DFPRSTIAYC TDAAFISIGS
LFGCSPITAF IESGAGIAEG GRTGLTAVVA GLCFIISIFF APIFASIPPW ATGCTLILVG
CMMARQITQV NWRYIGDVLP SFVVMTFIPF SYSVAYGLIA GLFVYTTLNG LIGLVVLLSG
HRIEPREYDL KEYWTWRGTG RAPWFVRAMR RGNSHSSPTS GDGHNNHSDT TATSSVPSEE
ESQRGFSVQH STKGDSAATE TLYRVHFNHD EDYDHYHHGH SSPLRGIAH
//
