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Database: UniProt
Entry: A0A0F9ZZ92_9BACT
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ID   A0A0F9ZZ92_9BACT        Unreviewed;       519 AA.
AC   A0A0F9ZZ92;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UR34_C0004G0007 {ECO:0000313|EMBL:KKP44266.1};
OS   candidate division WS6 bacterium GW2011_GWC1_33_20.
OC   Bacteria; Candidatus Dojkabacteria.
OX   NCBI_TaxID=1619089 {ECO:0000313|EMBL:KKP44266.1, ECO:0000313|Proteomes:UP000034302};
RN   [1] {ECO:0000313|EMBL:KKP44266.1, ECO:0000313|Proteomes:UP000034302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKP44266.1}.
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DR   EMBL; LBOV01000004; KKP44266.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKP44266; KKP44266; UR34_C0004G0007.
DR   PATRIC; fig|1619089.3.peg.251; -.
DR   Proteomes; UP000034302; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034302};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034302}.
FT   DOMAIN      217    351       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      427    496       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     225    232       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   519 AA;  59950 MW;  EA1C75F8A71C99F6 CRC64;
     MNIIGVPVPI DHILPSDFFK ILKYYISMDK IDFEKYITEM PKPNMESTTS TVEDFNTEDI
     WKIVSENLKM ILDRVEYNSW FSDTYLEDIR NGVATLSCSS EFKRGTILRD YSKFLQSCLT
     RATGQNLQLE ILIKSSGIKR KDTQDRYEFV STPQQSSVTL FSGIESDSKK YKQALSSARL
     NPKYTFDNFI VGPNSRLAEA VAQAVVHDIN NNNLTKSYNP VFYYGSTGVG KTHLMQAIGN
     EVIKKDPEKK VVYVSIEQFL NEMIEAIRTR KNEDFRSKYR EVDLLIIDDI QFVEDYPKTQ
     EELFHTFNTL YQANKQIILA SDRPPREIKN ITDRLRSRFE GGMVADIQIP DYETRVAILK
     QSLLDKNATV PDMYLELIAK NIENSVRELE GALNKVITLS KLGEVPTYEE VARILQLDIE
     SKRNKVTPLK VLDVTSSVFD ISVRYIKSKR RMAHISLARQ VVMYILRTDL ELPLETVAKE
     VNRTDHTTVL HACKQIEQKM KQDSRLAEKV ELCRKKIFF
//
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