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Database: UniProt
Entry: A0A0G0BLS0_9BACT
LinkDB: A0A0G0BLS0_9BACT
Original site: A0A0G0BLS0_9BACT 
ID   A0A0G0BLS0_9BACT        Unreviewed;       457 AA.
AC   A0A0G0BLS0;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UR21_C0003G0035 {ECO:0000313|EMBL:KKP32002.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWC2_31_9.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618586 {ECO:0000313|EMBL:KKP32002.1, ECO:0000313|Proteomes:UP000034803};
RN   [1] {ECO:0000313|EMBL:KKP32002.1, ECO:0000313|Proteomes:UP000034803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKP32002.1}.
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DR   EMBL; LBOI01000003; KKP32002.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKP32002; KKP32002; UR21_C0003G0035.
DR   PATRIC; fig|1618586.3.peg.207; -.
DR   Proteomes; UP000034803; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034803};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034803}.
FT   DOMAIN      155    287       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      367    436       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     163    170       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   457 AA;  50956 MW;  8D7D8A7D8C66EFFE CRC64;
     METVDKDKVW KDTLEVLRVS VSDATFGTWL THTHLSDVKE TGGRVVCEIG CNSIFVKSQV
     EQRYFGLIQD TLTKQFEKPT DLTFIVKPRH EEKQVTTNTP SPLFDQPKIN QEEINLATRR
     SNVRPSFTFE KFAVSGSNQL AHAAAEAIAQ SPGNAYNPLF IWGGVGVGKS HLMHAVGNSM
     ISKDTSSKII ACTAEDFTND IVDGIRNKTT AEVRKKYRKL DALFIDDIQF IAGKDTAQEE
     FFHTFNAVTS AGGQVILTSD RPPSEISKLE ERLKSRFEAG LIVDIAPPDF ELRCAIVQIK
     AEERGIKIDS EIVQLIAGNI DSARAIQGFI VNLFTQVNFK KLELTYDAVQ SILGKGNEKN
     ERVIKSNPED VINIVSKYYS VGKKQLLGES RARPIARPRQ MLMYLLKTQL GIPYQEVGRL
     IGGRDHTTVM HAVNKIQELA SSSVDIQEDI RGIKKSL
//
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