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Database: UniProt
Entry: A0A0G0CQL3_9BACT
LinkDB: A0A0G0CQL3_9BACT
Original site: A0A0G0CQL3_9BACT 
ID   A0A0G0CQL3_9BACT        Unreviewed;       482 AA.
AC   A0A0G0CQL3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   05-JUL-2017, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UR43_C0004G0111 {ECO:0000313|EMBL:KKP53570.1};
OS   candidate division TM6 bacterium GW2011_GWF2_33_332.
OC   Bacteria; Candidatus Dependentiae.
OX   NCBI_TaxID=1619080 {ECO:0000313|EMBL:KKP53570.1, ECO:0000313|Proteomes:UP000034634};
RN   [1] {ECO:0000313|EMBL:KKP53570.1, ECO:0000313|Proteomes:UP000034634}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKP53570.1}.
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DR   EMBL; LBPE01000004; KKP53570.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKP53570; KKP53570; UR43_C0004G0111.
DR   PATRIC; fig|1619080.3.peg.592; -.
DR   Proteomes; UP000034634; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034634};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034634}.
FT   DOMAIN      179    307       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      390    459       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     187    194       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   482 AA;  55155 MW;  31B773577C183B52 CRC64;
     MQLVWNEFLK IIEKEAGNQV VETWFKAVTL EQWNKETNSA FLLMPNPFVQ KWIEEHYSEL
     IKMHLSRLLC AKNLTLFLTC KKDEKKLIPA SHLQKQILIN TNDELFAASS EIKQILNQSL
     EKTNKSTALQ IKPQNSIVKR KKNFNKLNEI HTFDSFVVGP NNALAHAAAL AVSQKPGIVY
     NPLFIYGGTG LGKTHLLHAI GNEAKKLNPS CFVYYETSDN FIYEFVNSIK TDQVRLFREK
     YQKADILLLD DIQFFSKKEQ TQEAFFHIFD SLQQHNKQVV FSSDTAPKDI SGLQDRLKSR
     LQSGLIADIY MPTFETKMAI LNKKAAFHSV VLNEEVTKFI ASKPASSIRE LEGYLIRLSA
     MSSLTTQAIS LELAKQILKE DNIEEKQNVS AETIIKAVAK YYTLSVSDLK SKSRNKKLAF
     ARQIVFYMMK KFTLYSLQSI GEYLGKKDHT TVLHAITKIE RLKENDQNVT TKLKAIENLI
     LK
//
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