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Database: UniProt
Entry: A0A0G0E3N2_9BACT
LinkDB: A0A0G0E3N2_9BACT
Original site: A0A0G0E3N2_9BACT 
ID   A0A0G0E3N2_9BACT        Unreviewed;       442 AA.
AC   A0A0G0E3N2;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=US11_C0007G0016 {ECO:0000313|EMBL:KKQ01523.1};
OS   Candidatus Roizmanbacteria bacterium GW2011_GWA2_36_23.
OC   Bacteria; Candidatus Roizmanbacteria.
OX   NCBI_TaxID=1618480 {ECO:0000313|EMBL:KKQ01523.1, ECO:0000313|Proteomes:UP000034344};
RN   [1] {ECO:0000313|EMBL:KKQ01523.1, ECO:0000313|Proteomes:UP000034344}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKQ01523.1}.
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DR   EMBL; LBRS01000007; KKQ01523.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKQ01523; KKQ01523; US11_C0007G0016.
DR   PATRIC; fig|1618480.3.peg.504; -.
DR   Proteomes; UP000034344; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034344};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034344}.
FT   DOMAIN      138    267       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      348    417       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     146    153       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   442 AA;  50148 MW;  A2275429B9B69A4D CRC64;
     MLSSFWEGFL QYLGKDKEKA PVLLSVLRQV KPIEITESEI IIGCDNQGVK FFLEKRTLEI
     EQNLLIFTKK KLKVRFLITE KKSKKEPPPL LNFQPSVEDI FLKSGLHLKY SFENFAVSST
     NQVAYAAAQA VSQNLGSAYN PLFLYGGVGV GKTHLAQSVA RKILEANQNK KVLFCPGDRF
     TNELIESIRE KSTPRFRKRY RYLNLLIVDD IQFIAGKQTV QEEFFHTFNS IASSGGQIIL
     TSDRPPSDIK NLEDRLRSRF SGGLTVDIQP PDFELRTAIV LIKAKEKKIE IDIEAAKLIA
     EQVADSRELE GALLSLYAKI LGSKEQIDLE TVASFFTQKE NIKVKKISAP DVVRAVCFFY
     NIKPSHLKGE TRASSVVLPR QVTMYLLRKE LRLKFDEVAY ILKRKDHTTV MHAVEKITRL
     LIKDPSLKQE VVGITKSLFS ST
//
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