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Database: UniProt
Entry: A0A0G0EPC1_9BACT
LinkDB: A0A0G0EPC1_9BACT
Original site: A0A0G0EPC1_9BACT 
ID   A0A0G0EPC1_9BACT        Unreviewed;       457 AA.
AC   A0A0G0EPC1;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   05-JUL-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UR66_C0001G0014 {ECO:0000313|EMBL:KKP69132.1};
OS   Candidatus Moranbacteria bacterium GW2011_GWE1_35_17.
OC   Bacteria; Candidatus Moranbacteria.
OX   NCBI_TaxID=1618707 {ECO:0000313|EMBL:KKP69132.1, ECO:0000313|Proteomes:UP000034945};
RN   [1] {ECO:0000313|EMBL:KKP69132.1, ECO:0000313|Proteomes:UP000034945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKP69132.1}.
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DR   EMBL; LBQA01000001; KKP69132.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKP69132; KKP69132; UR66_C0001G0014.
DR   PATRIC; fig|1618707.3.peg.16; -.
DR   Proteomes; UP000034945; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034945};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034945}.
FT   DOMAIN      155    287       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      367    435       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     163    170       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   457 AA;  52271 MW;  91B57505DFECA7D8 CRC64;
     MNNEDLWKAV LGEIELSLSR PQFITWFKDT FILSNENGKV IIGVPNGFSK EWLENKFNTN
     IIKALKNFQE NIIEVSCAIY SPQEKPSRNI DGAGKNTSGV QTINLKNTKT LTPQINFFQN
     TNLNSRYTFD SFVIGENNEL ARAACFAVSQ NPGTQYNPLF IYGDVGLGKT HLLQSIGNEI
     LKSDPNKNII YISSEGFTTE LVNSIKNQTI DKFKNKYQQA DLLIIDDIQF ISGKEKTQDI
     FFHIFNSLYQ LNKQIVISSD RPPSHIQILE DRLRSRFEGG MITDIGNPDL ETRLAILQTK
     LNEKKFFLND DILKFIAENI KNNIRELEGA LNKLVATFEL NKKTPTIEET KKILSSILVS
     KQESAITKKD IINSVLGFFE LTKEDLMSSS RKKKVALPRQ ITMFLFKREL KMSYPEIGEY
     FKRDHTTALH AFNKISKDIQ NNSKTSTDVE FIFKSLR
//
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