ID   A0A0G0EX57_9BACT        Unreviewed;       542 AA.
AC   A0A0G0EX57;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Long-chain-fatty-acid-CoA ligase {ECO:0000313|EMBL:KKQ11538.1};
GN   ORFNames=US22_C0022G0002 {ECO:0000313|EMBL:KKQ11538.1};
OS   candidate division TM6 bacterium GW2011_GWF2_36_6.
OC   Bacteria; Candidatus Dependentiae.
OX   NCBI_TaxID=1619082 {ECO:0000313|EMBL:KKQ11538.1, ECO:0000313|Proteomes:UP000034938};
RN   [1] {ECO:0000313|EMBL:KKQ11538.1, ECO:0000313|Proteomes:UP000034938}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKQ11538.1}.
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DR   EMBL; LBSD01000022; KKQ11538.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G0EX57; -.
DR   PATRIC; fig|1619082.3.peg.272; -.
DR   Proteomes; UP000034938; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:KKQ11538.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        96..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          45..409
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          459..534
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   542 AA;  60319 MW;  1BA0F5D4B3625F67 CRC64;
     MSNSFFWKDD SNHSNIESSI FDKIQNDFIK NGDLAYAGEL LKIAYEKYPN NIALIHQNQS
     LTYKEFYFRS ILFSRKLKAS GIKPRDKVLI FSENSIAFYI AYFAVWQIGA IAVPVNIFLH
     AKELSYIIKD SEPVAIICSS LLKSNIEDLV TQNYLDNLPA IFTNQDIDFV SPIPGDKSSP
     DKSTSDTELL SSFEVERLET DELCLLLYTS GTTGTPKGVM LSSRNIMTNA IQAYSRFNMM
     GLTDKERFFC VLPLFHVFAQ NACLWLPLIT GSTIIIVQKI DRKLILEGLK HQPTLFLGFP
     ALYGLLCMMK TAPLDSVKVF VSGADMLPDK IRQAFGMVYG RKICAGYGLS EASPIVAVNY
     CNNSMPTHFV GRPLAGIECD IRDDDGKSLP HGTIGHLWIR GGNIMIGYYK SSAATAKVMD
     GNWLNTGDLG LVDSRRYLAI SGRVKDIIIH KGFNIYPAEI ENVLLRHPDV FKAAVVGQED
     SDSGQIPVAF VAIKSKNNGI EASLRSLCTN NLAAYKVPRK FVCVEDLPMN STGKVDKKQL
     RI
//