ID A0A0G0HIW0_9BACT Unreviewed; 513 AA.
AC A0A0G0HIW0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Translation initiation factor IF-2 {ECO:0000313|EMBL:KKQ12009.1};
GN ORFNames=US24_C0007G0009 {ECO:0000313|EMBL:KKQ12009.1};
OS candidate division WS6 bacterium GW2011_GWC2_36_7.
OC Bacteria; Candidatus Dojkabacteria.
OX NCBI_TaxID=1619091 {ECO:0000313|EMBL:KKQ12009.1, ECO:0000313|Proteomes:UP000034075};
RN [1] {ECO:0000313|EMBL:KKQ12009.1, ECO:0000313|Proteomes:UP000034075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ12009.1}.
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DR EMBL; LBSF01000007; KKQ12009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0HIW0; -.
DR PATRIC; fig|1619091.4.peg.114; -.
DR Proteomes; UP000034075; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR CDD; cd03692; mtIF2_IVc; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF5; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KKQ12009.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 13..182
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 513 AA; 55839 MW; 5533FCD51E35F25F CRC64;
MSKKSQNTTQ EGERVPIVTI LGHVDHGKTT ILDNIRKSDV QGCEVGGITQ KVSVFTVCVK
DGKKITFIDT PGHEAFDLMR SRGGSIADIV LLIIAADDGV QPQTKESIEI INRSTAKPIV
VINKCDLPDM DIPKIKRELV SNGMQVEGLG GSIPVIEVSG KTGKGIPELL DLILLVAEVE
GLQEREELPK GVIGKAFVLE SIKDQSKGNV SSLALISGHI CEGDLFGYRI GKEYFIEKVK
GVIAEDNADL CLLSGGCGGK ILGVSNSLEL GTEVFVLEKN DEKFLKSLYK EVSTEAITEE
EALEDFFGDQ EVTNDKFFNV IVKSSSEGSL EALKNSLSKI EEDGYTAKII KSGVGNITLR
DVEMGSLSRA IVLGFEVGME NGVNEYAKNN KVLVRTYDII YKLLEEVNDV VSLMSLPKDV
EEEIGKAVVK TVFILSNGTK VFGSRVESGI MKRDCRCDVV RKDEILGSGK IKSLRINKDT
VTEAKTGFDC GIQLDADIDI QEGDEIYCFK VVK
//
