ID A0A0G0I2M6_9BACT Unreviewed; 521 AA.
AC A0A0G0I2M6;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Radical SAM family Fe-S protein {ECO:0000313|EMBL:KKQ48817.1};
GN ORFNames=US68_C0023G0002 {ECO:0000313|EMBL:KKQ48817.1};
OS Candidatus Shapirobacteria bacterium GW2011_GWE1_38_10.
OC Bacteria; Candidatus Shapirobacteria.
OX NCBI_TaxID=1618488 {ECO:0000313|EMBL:KKQ48817.1, ECO:0000313|Proteomes:UP000034231};
RN [1] {ECO:0000313|EMBL:KKQ48817.1, ECO:0000313|Proteomes:UP000034231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ48817.1}.
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DR EMBL; LBTX01000023; KKQ48817.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0I2M6; -.
DR Proteomes; UP000034231; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 31..181
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 238..469
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 521 AA; 59552 MW; 82917078F5F29050 CRC64;
MSGTGLNGPT NYINKYLNDF MKHFRVLLIN PPNSVPIKSN FVINVFQPLG LAYVASSLEK
HKYSVEIFDA LALGFDQEKI IASRKVIGAD YQTIKNKIID YRPDLVGIAT PFSFQSFESH
QIAKIVKKIN PKIITLAGGT HATIQPDEML NDKNFDYLIR GEGEYATVEL LKALEKKTSL
KNISSLSYRN KQNKIIHNPR SLPIQKLDAL PFPARHLLPM DKYLQAAKKG RVVEGMLAFG
HKRTSIFTSR GCPFNCTFCS VHLTMTRMWR GRSPENVLKE IKECVYKYGI KYFDILDDNF
TLDPKRAKKI CRLIIKEKLN IQWSTPNGIR ADRVDETLIK LMKKAGCIQV KVAPESGSPL
VLKNIIKKHL DLDMVKKTVS LCKKHHLSVE AFFVVGFPEE TIDDIYKTIS FAKELRRLGC
DYCYFFIATP YYGTEMYADA VKKGYLDESR YHLNKIITTT NKSLLKSPNY THKKLFELLK
VAAKVNPPIT KIRLKSGLKM LILDPKRILT YSFGYLRNFL P
//
