ID A0A0G0MB18_9BACT Unreviewed; 701 AA.
AC A0A0G0MB18;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504, ECO:0000256|RuleBase:RU003587};
GN ORFNames=UT23_C0011G0016 {ECO:0000313|EMBL:KKQ97545.1};
OS Candidatus Woesebacteria bacterium GW2011_GWA1_39_12.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1618549 {ECO:0000313|EMBL:KKQ97545.1, ECO:0000313|Proteomes:UP000034325};
RN [1] {ECO:0000313|EMBL:KKQ97545.1, ECO:0000313|Proteomes:UP000034325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033, ECO:0000256|RuleBase:RU003587}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- SIMILARITY: Belongs to the UvrB family. {ECO:0000256|ARBA:ARBA00008533,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ97545.1}.
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DR EMBL; LBWA01000011; KKQ97545.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0MB18; -.
DR PATRIC; fig|1618549.4.peg.935; -.
DR Proteomes; UP000034325; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd17916; DEXHc_UvrB; 1.
DR CDD; cd18790; SF2_C_UvrB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003587};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769,
KW ECO:0000256|RuleBase:RU003587};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003587};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881,
KW ECO:0000256|RuleBase:RU003587};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW SOS response {ECO:0000256|RuleBase:RU003587}.
FT DOMAIN 25..151
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 467..617
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 667..701
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
SQ SEQUENCE 701 AA; 80580 MW; CF7FE112ED8DC121 CRC64;
MNTFKLKSDY KPIPDQEKAI NALCGGVQNG IDYQVLLGVT GSGKTFTVAN VIERLQRPAL
IISHNKTLAA QLYQEFRDFF PENAVSFFVS YYDYYQPEAY IPSTDTYIEK DSDINELIDK
LRLAATTNLL TRRDTIVVAS VSCIYNIGSP REYGHFVFEI SKGVKIGRKQ IIDRLVDLQY
ERGDFGFHRG TFRVMGNTID IYPAYQDEGV RLELGEDNIK DLTIINPVSG SQITDHKSPV
TNFVLYPAKH YVTDPSKNKN VFEEIKRDLA ERITFFKKNG KELEAYRLQN RVKYDLEMIS
ELGYVKGIEN YSRYFDGRAP GDPPYTLLDY YQEPYNNDWL TFIDESHITF PQIRGMYNGD
VARKNLLIDY GFRLPAAYDN RPLKFEEFMR RIPGFIATSA TPSEWEVGMA RESASILRSK
VTRFGKPVPY QVRSTLDEPG VVQQLLRPTG IPDPKVEIRS ARNQVSDVID EIKKVAKRGQ
RTLVTTLTKR TAEDLSQYLI EQGMKVHYLH SDVATLERSD ILDDLRRGKY DCIIGVNLLR
EGLDLPEVSL VAILDADKEG FLRSEVSLIQ TMGRAARHVE GRVILYADNV TGSMERAIAE
VERRRKYQIK VNKKYGIKPT SITKPIRERL VEEEEESVLD KLFEKTEKTY LKLPDIELDS
LTPMDKRKLT VKLRREMKLA AQDLNFELAA EIRDKIKELE F
//
