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Database: UniProt
Entry: A0A0G0NCU6_9BACT
LinkDB: A0A0G0NCU6_9BACT
Original site: A0A0G0NCU6_9BACT 
ID   A0A0G0NCU6_9BACT        Unreviewed;       462 AA.
AC   A0A0G0NCU6;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=US96_C0021G0003 {ECO:0000313|EMBL:KKQ74936.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWB1_38_5b.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618569 {ECO:0000313|EMBL:KKQ74936.1, ECO:0000313|Proteomes:UP000034181};
RN   [1] {ECO:0000313|EMBL:KKQ74936.1, ECO:0000313|Proteomes:UP000034181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKQ74936.1}.
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DR   EMBL; LBUZ01000021; KKQ74936.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKQ74936; KKQ74936; US96_C0021G0003.
DR   PATRIC; fig|1618569.3.peg.548; -.
DR   Proteomes; UP000034181; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034181};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034181}.
FT   DOMAIN      155    283       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      367    436       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     163    170       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   462 AA;  51364 MW;  6876AB7659C982FF CRC64;
     MDKDKIWHEV LESLKVSISS AAFSTWLNQT HLSALKELDT QPPRFIVEIG CQTTFVRQTV
     EVRYFGLIQE ALTQKLGMPC DLSFTTRQNP NTGVFNTNKV LAPLFDEKNL GQALIEKLSQ
     SHLRPFFTFD NFAVSASNQM AWAAAQAVAE KPGSTYNPLF LWGGVGVGKT HLMNAVGLSI
     INSIPESKIL LCTGEDFTND IVAGIRTKTT HAFRDKYRRL ACLLIDDIQF IAGKDSVQEE
     FFHTFNAVTG AGGQIILTSD RPPSDITKLE ERLRSRFEAG LIVDISPADF ELRCAIVQIK
     AAEKSLEIPT ELVHLLAGNL DTARKINGVL TRLISEVKLQ KRVINEELIK SLIGKGSNGD
     TINKNIRADD VVEAVCSHFT ISKRALMGDG RSRIIARPRQ ILMYFLRIEL GLPLEEVGKM
     IGGRDHTTVM HAVDKITNLA SIDVNIREDL MGIKRRFSGQ KT
//
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