ID A0A0G0PFW4_9BACT Unreviewed; 348 AA.
AC A0A0G0PFW4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN ORFNames=UT57_C0020G0006 {ECO:0000313|EMBL:KKR27079.1};
OS Microgenomates group bacterium GW2011_GWC1_39_7.
OC Bacteria.
OX NCBI_TaxID=1618515 {ECO:0000313|EMBL:KKR27079.1, ECO:0000313|Proteomes:UP000034535};
RN [1] {ECO:0000313|EMBL:KKR27079.1, ECO:0000313|Proteomes:UP000034535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-
CC methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:16857, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:13674,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:85452, ChEBI:CHEBI:137933; EC=2.1.1.113;
CC Evidence={ECO:0000256|ARBA:ARBA00001893};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family. N(4)
CC subfamily. {ECO:0000256|ARBA:ARBA00010203}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR27079.1}.
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DR EMBL; LBXH01000020; KKR27079.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0PFW4; -.
DR Proteomes; UP000034535; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0015667; F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR017985; MeTrfase_CN4_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR010093; SinI_DNA-bd.
DR NCBIfam; TIGR01764; excise; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00093; N4_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KKR27079.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 101..335
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 348 AA; 39898 MW; E1B4A7F70C749738 CRC64;
MEDYKERKYL SSIEAAMYLN TTVSTIHHLA KSGEINSVIS GSGQKRFNLK DLKKYLTSLP
KKAKPIQKKS SIYTELEVGN TVQKIYRKSS IKMSDLEDES VHLMLTSPPY FNAKMYSKRP
IKEDLGNIHD LDEWFETITE VWREVFRVLQ PGRKAFINIM NLPVRGNGTF RTLNLVGRTV
DVMEQIGFIF KRDIIWQKTN GVRAHFGTYP YPGGILINNM HEFILEFNKP ERKNFNKYAH
LSRAQKESSR MDKNFWLSIK NSDVWVMKPE NSGGNRSHVA PFPFELPFRI IKAFSFIGET
ILDPFLGSGT ALKAAADLGR NGVGYELSKE IADDAITNLK KQQIKLFA
//
