GenomeNet

Database: UniProt
Entry: A0A0G0PIQ8_9BACT
LinkDB: A0A0G0PIQ8_9BACT
Original site: A0A0G0PIQ8_9BACT 
ID   A0A0G0PIQ8_9BACT        Unreviewed;       455 AA.
AC   A0A0G0PIQ8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UT23_C0006G0015 {ECO:0000313|EMBL:KKQ97974.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWA1_39_12.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618549 {ECO:0000313|EMBL:KKQ97974.1, ECO:0000313|Proteomes:UP000034325};
RN   [1] {ECO:0000313|EMBL:KKQ97974.1, ECO:0000313|Proteomes:UP000034325}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKQ97974.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LBWA01000006; KKQ97974.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKQ97974; KKQ97974; UT23_C0006G0015.
DR   PATRIC; fig|1618549.4.peg.595; -.
DR   Proteomes; UP000034325; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034325};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034325}.
FT   DOMAIN      153    285       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      366    434       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     161    168       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   455 AA;  50663 MW;  5222C71F7C07F965 CRC64;
     MEIDTKQLWR SLLENVKVSV SAPVFNTWFS QTHLVNLKKD NQRYVAEIGC NNVFVKNTIE
     NRYFGLIQDV LSSSLELPCE LLFVIKENPD QRKNGLSLTP LFEEPTVKSQ EITNIARNVG
     LRPGFTFANF AVSSSNQMAH AAAEAVANDL SSAYNPLFVW GGVGVGKTHL MHAIGYSAIE
     KDQETKLYCC TGEQFTNDIV EGIRNKTTSA VRQKYRKLKA LLLDDIQFIA GKEGIQEEFF
     HTFNALVSSG GQVILTSDRP PSEISKLEER LKSRFEAGLI VDIAPPDFEL RCAITQIKAK
     EKGVELAMDM AQTIAGNLES ARKIEGFLIK LFSEARIKNV EITPEFIESQ LGKGGETNGQ
     ILKKSSPNDV ISAVSKHFSL NKKSLLGASR SRPVARPRQV LMYILRIDLG LPLEEVGRIV
     GRDHTTVMHA VNKITHMVSS DVNIREDIRG IKNML
//
DBGET integrated database retrieval system