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Database: UniProt
Entry: A0A0G0QRM3_9BACT
LinkDB: A0A0G0QRM3_9BACT
Original site: A0A0G0QRM3_9BACT 
ID   A0A0G0QRM3_9BACT        Unreviewed;       468 AA.
AC   A0A0G0QRM3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UT30_C0010G0031 {ECO:0000313|EMBL:KKR04267.1};
OS   Candidatus Uhrbacteria bacterium GW2011_GWF2_39_13.
OC   Bacteria; Candidatus Uhrbacteria.
OX   NCBI_TaxID=1618995 {ECO:0000313|EMBL:KKR04267.1, ECO:0000313|Proteomes:UP000033935};
RN   [1] {ECO:0000313|EMBL:KKR04267.1, ECO:0000313|Proteomes:UP000033935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKR04267.1}.
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DR   EMBL; LBWG01000010; KKR04267.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKR04267; KKR04267; UT30_C0010G0031.
DR   PATRIC; fig|1618995.3.peg.550; -.
DR   Proteomes; UP000033935; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033935};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033935}.
FT   DOMAIN      163    295       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      375    444       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     171    178       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   468 AA;  53528 MW;  B320F4902D701C67 CRC64;
     MNTNELWQAV LGELELSLSK ANFTTWFKNT FISDLEEHAI TIGVPNMFTK AWLEKKYTKE
     ILRSLQELTK NSIKQLSYRV QSRPTNPQGM PLFEKGTNPE PSPSPSNQQA SYYQPQQTHE
     VKEIRTGEFS LNGKYCFETF IVGKQNELAH AAAQAVCAQP GGIYNPLFIY GGVGLGKTHI
     LQAIGNELIR KNANTKILYV TCERFTNDFI GALRSNRIVE FKNRYRTVDV LLVDDIQFIT
     GKEGTQEEFF HTFNQLYQNN KQIVISSDRP PKTIPALEDR LVSRFECGML ADVGSPDFET
     RCAILDTKCL EKQYSLERDI LHHIATVVQT NVRELEGALN KVIAFHQFKN TRPTLESVKP
     ILSSFQPTST KKNITPKQLI ITVANYFDIH MDDLLGKSRQ KRLAFPRQIV MYIMREEMKA
     SYPSIGMELG GRDHTTAMHA YDKIMTCLLE DEKLQHDIEL IKQKLYAL
//
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