ID A0A0G0TRD4_9BACT Unreviewed; 434 AA.
AC A0A0G0TRD4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 22.
DE SubName: Full=Putative UDP-glucose/GDP-mannose dehydrogenase enzyme family {ECO:0000313|EMBL:KKR79559.1};
GN ORFNames=UU24_C0006G0053 {ECO:0000313|EMBL:KKR79559.1};
OS Candidatus Nomurabacteria bacterium GW2011_GWA2_40_9.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1618734 {ECO:0000313|EMBL:KKR79559.1, ECO:0000313|Proteomes:UP000034749};
RN [1] {ECO:0000313|EMBL:KKR79559.1, ECO:0000313|Proteomes:UP000034749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR79559.1}.
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DR EMBL; LBZW01000006; KKR79559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0TRD4; -.
DR PATRIC; fig|1618734.3.peg.264; -.
DR Proteomes; UP000034749; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 328..423
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 434 AA; 48552 MW; D2F769D3E9E55CCF CRC64;
MMDLNQKLKE RKAKVAILGL GYVGLPLCLE FLESGFEVIG LDVNENKVKS LNRAESYVTD
ISNEELLKAL NTKRFRVSSD FSLLKEVDTV SVCVPTPLRK TKEPDISFII SAAENIGKYL
KKGQLVVLES TTYPGTTEEI VLPELEKSGL KVGKDFFLAF SPERIDPGNL KFNLKNTPKI
VGGITSNCTE MAVSLYSTIV NKVIPVSSTQ AAEMVKLLEN TFRAVNIGLV NEIALMADKL
NLDVWEIIDA AASKPFGFLP FYPGPGLGGH CIPVDPHYLS WKLRELNYNP KFIDLAQEIN
SKMPELVVDK IAFALNKFKK ALNGSKVLVL GIAYKKDVGD VRESPALDII ELLRQKGAQV
SYEDKYCPFL HHEHVELKSI TLDYSTFSQY DCIAIVTDHS YFDYEKVVEF SSVVVDCRNA
TRWVKSHKDK IIKI
//
