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Database: UniProt
Entry: A0A0G0UI48_9BACT
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ID   A0A0G0UI48_9BACT        Unreviewed;       451 AA.
AC   A0A0G0UI48;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UU32_C0007G0003 {ECO:0000313|EMBL:KKR87171.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWB1_41_10.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618577 {ECO:0000313|EMBL:KKR87171.1, ECO:0000313|Proteomes:UP000033858};
RN   [1] {ECO:0000313|EMBL:KKR87171.1, ECO:0000313|Proteomes:UP000033858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKR87171.1}.
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DR   EMBL; LCAE01000007; KKR87171.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKR87171; KKR87171; UU32_C0007G0003.
DR   PATRIC; fig|1618577.3.peg.145; -.
DR   Proteomes; UP000033858; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033858};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033858}.
FT   DOMAIN      150    281       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      362    430       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     158    165       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   451 AA;  50109 MW;  E7D71B758F028078 CRC64;
     MDLKEIWKDS LEIIKISVST ANFQAWFPQT FIDSIREVGK KSVIEIGCPT AYSKNTIESR
     YFGLVQDGLS KTMDKPCEVI FLVKQNPDKI NLTKLDTPLF TDKKESENLL PLFQKTRIRP
     SFTFKDFAVS GSNQMAFAAA EAVATSPGTA YNPLFIWGGV GVGKTHLMHA VGRAILEKMG
     DINILACTAE DFTNDIVEGI RNKTTPEVRK KYRKLNALLI DDIQFIGGKD TAQEEFFHTF
     NAVTSAGGQI IMTSDKPPTE IAGLEERLKS RFEAGLTVDI GAPDFELRCA ITQIKAEQKK
     LNLDTEQVQL IAANVESARK IEGILTKLLT EIHVKNIPIT KEMVESLLGK GVEGNGASVK
     ATPGETIDIV SKYYQVGKKN LLGDTRTRLI ARPRQVLMYL LRTHLRVSLE EVGRLVGRDH
     TTVMHGVGKI AQLAMTDVQI REDILRIKKS L
//
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