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Database: UniProt
Entry: A0A0G0WN44_9BACT
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ID   A0A0G0WN44_9BACT        Unreviewed;       239 AA.
AC   A0A0G0WN44;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 16.
DE   SubName: Full=Chromosomal replication initiator protein DnaA {ECO:0000313|EMBL:KKS13502.1};
GN   ORFNames=UU70_C0014G0009 {ECO:0000313|EMBL:KKS13502.1};
OS   Candidatus Yanofskybacteria bacterium GW2011_GWA1_41_6.
OC   Bacteria; Candidatus Yanofskybacteria.
OX   NCBI_TaxID=1619020 {ECO:0000313|EMBL:KKS13502.1, ECO:0000313|Proteomes:UP000034380};
RN   [1] {ECO:0000313|EMBL:KKS13502.1, ECO:0000313|Proteomes:UP000034380}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKS13502.1}.
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DR   EMBL; LCBQ01000014; KKS13502.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKS13502; KKS13502; UU70_C0014G0009.
DR   PATRIC; fig|1619020.3.peg.138; -.
DR   Proteomes; UP000034380; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034380};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034380}.
FT   DOMAIN      143    212       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   239 AA;  27488 MW;  41C00CD4AECEA5B6 CRC64;
     MIDDVQFIAG KEKTQDIFFS TFNELYSKNK QIILSSDRPP QTIPALEERL RSRFQGGMVA
     DVGLPDFETR LAILKLKAAE RGYELNLEVL TYIATHIQKN VRELEGALNR VVAFGQIYNR
     VPEIKEVKNI LNTYLSTPYR KTSPQTILKS VADFYSISLA DIVKRSRKKE IVKPRQIAMF
     LLREETKLSF PEIGQKLGGR DHSTVIHACE KIKNEISVDE PLKQELILIK ERVYNSFDK
//
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