ID A0A0G0ZJP4_9BACT Unreviewed; 292 AA.
AC A0A0G0ZJP4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 33.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN ORFNames=UV11_C0001G0060 {ECO:0000313|EMBL:KKS48965.1};
OS Candidatus Giovannonibacteria bacterium GW2011_GWF2_42_19.
OC Bacteria; Candidatus Giovannonibacteria.
OX NCBI_TaxID=1618659 {ECO:0000313|EMBL:KKS48965.1, ECO:0000313|Proteomes:UP000034036};
RN [1] {ECO:0000313|EMBL:KKS48965.1, ECO:0000313|Proteomes:UP000034036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|ARBA:ARBA00005952,
CC ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS48965.1}.
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DR EMBL; LCDF01000001; KKS48965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0ZJP4; -.
DR STRING; 1618659.UV11_C0001G0060; -.
DR PATRIC; fig|1618659.3.peg.67; -.
DR Proteomes; UP000034036; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR CDD; cd00619; Terminator_NusB; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF00293; NUDIX; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW ECO:0000256|HAMAP-Rule:MF_00073};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00073}.
FT DOMAIN 148..283
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 292 AA; 32649 MW; 2D7D96DA7D19F9CC CRC64;
MQSLFQWDFS GRNDAAADEI VEYHTKEFAP GLEDDNFARE LVKGVLKNRE KLDSIIEKAA
PEWPLEQVAI VDRNVLRLGL YELLFGNRTE VPPKVAINEA IELAKTYGSD SSGKFVNGVL
GTVYREIGEP GKDETTKKKG PVDLKDLPIE TLGGGVVYRD EDGKIFFGLV HDVFGYWTLS
KGHLEENEEP IEGAKREVGE ELGVSNLIAG ENLGTNEYVA SDPKIGKVRR QVTYFLFKAN
TKELKDLTTG EHSGLDDAKW FFSEEIAQLK TYDDIKPLLN KALDIIKQKP KA
//
